A rare case of Takayasu's arteritis in pregnancy

Successful Management of Takayasu’s Arteritis with Pulmonary Hypertension in Pregnancy: A Rare Case

“…TA was first described in 1908 by the Japanese ophthalmologist Mikito Takayasu. It has variable geographical distribution with the greatest prevalence in Asians, especially Japan [5] [6]. Women are affected in 80% -90% of cases with a mean age of presentation in the second and third decade of life [1] [4], reflected in a synonym for TA as ''young female arteritis''.…”

“…The major risk for the fetus is intrauterine growth restriction and in utero fetal demise. The risk of fetal death is greatest in the third trimester, especially in those with uncontrolled hypertension [5] [6].…”

“…As per European League Against Rheumatism (EULAR), initial high doses of glucocorticoids were used for the remission of the disease and an immunosuppressive agent is used as an adjunctive therapy. EULAR recommends the starting dose of glucocorticoids 1 mg/kg body weight for four weeks and then to taper them off [6]. The patient was given various therapy including hypertension control, i.e.…”

“…Women are affected in 80% -90% of cases with age of onset below 40 years [1] [4]. TA does not worsen or improve with pregnancy, but has adverse effect on pregnancy in the form of superimposed preeclampsia, abortion, intrauterine fetal death, intrauterine growth restriction, abruption and congestive heart failure [5] [6]. Because the disease is common in women of childbearing age, management of pregnancy in these patients becomes an important issue; however optimal management for pregnant patients with this disease has not yet been established.…”