A rare case of oral melanoacanthoma

Tandon, Aanchal; Srivastava, Abhinav; Jaiswal, Rakesh; Bordoloi, Bharadwaj

doi:10.4103/jomfp.jomfp_96_18

Cited by 5 publications

(4 citation statements)

References 6 publications

(30 reference statements)

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“…Melanophages are located within the dermis underneath a tumor ( Figure 4) 1 . In contrast to common SKs, these lesions rarely occur on oral mucosa 33 .…”

Section: Pathogenesismentioning

confidence: 87%

Recent advances in managing and understanding seborrheic keratosis

Wollina

2019

F1000Res

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Seborrheic keratosis (SK) is a common benign epidermal tumor with predominance in adult patients. Whereas common SKs are more frequent in Caucasians, dermatosis papulosa nigra is more prevalent in patients with a Fitzpatrick skin type of at least 3. There seems to be a link between extrinsic skin aging and the occurrence of SK. Mutations of fibroblast growth factor receptor 3 and other signaling molecules are a frequent finding in SK lesions. However, this does not translate into any malignant potential. Viral infections are particularly common in genital lesions, although their pathogenetic relevance for SK is questionable. Different histologic and clinical subtypes have been identified. The great variability of SKs raises some difficulties in diagnosis. Dermoscopy is the preferred non-invasive diagnostic method, in particular to differentiate pigmented SKs from other pigment tumors, including cutaneous melanoma. Eruptive SKs can be a paraneoplastic condition known as the Leser–Trélat sign. New targeted cancer treatments can cause a pseudo-Leser–Trélat sign. The treatment in practice is mainly minor surgery, including cryosurgery, shave excisions, and laser-assisted removal. The medical approaches have only limited effects. Recently, two formulations for topical therapy have been evaluated: a product with 40% hydrogen peroxide (HP40) and an aqueous nitric–zinc complex. Based on clinical trials, HP40 seems to be a promising alternative to surgery, in particular for facial lesions.

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“…Melanophages are located within the dermis underneath a tumor ( Figure 4) 1 . In contrast to common SKs, these lesions rarely occur on oral mucosa 33 .…”

Section: Pathogenesismentioning

confidence: 87%

Recent advances in managing and understanding seborrheic keratosis

Wollina

2019

F1000Res

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“…Окрім шкірних проявів описані випадки появи даного новоутворення на слизових оболонках ротової порожнини і повік [2,14,16,18]. Так, Gonçalves et al описали множинні прояви оральної меланоакантоми, що локалізувались на слизовій ясен верхньої щелепи і внутрішній поверхні слизової нижньої губи [6].…”

Section: вступunclassified

Clinical Picture and Diagnostic Algorithm for the Management of Patients With Melanoacanthoma

Makurina¹

2021

D&V

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The objective of this study is to describe a clinical case of melanoacanthoma, as a rare variant of seborrheic keratosis, which hides the ability to mimic melanoma and determine the diagnostic algorithm for patient management, further doctor’s tactics, based on clinical-dermatoscopy-pathomorphological features. Materials and methods. Visual assessment of the neoplasm using the ABCDE algorithm, dermatoscopic examination to determine characteristic patterns and the use of a scale of 11 criteria according to S. Menzies, pathomorphological and immunohistochemical studies. Results. A 32-year-old woman has a neoplasia suspicious for melanoma on the basis of a comprehensive visual and dermatoscopy examination. As a result of excisional removal and pathomorphological conclusion, it is legitimate to formulate the final diagnosis in the context of variation of seborrheic keratosis. Conclusions. Melanoacanthoma is a rare variant of seborrheic keratosis that clinically resembles melanoma and requires an individualized diagnostic algorithm.

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“…Fibrolipoma, distinguished by a dense network of fibrous collagen and mature fat cells, is classified by the World Health Organization as a rare histological subtype of traditional lipomas. [3] The occurrence of fibrolipoma in the lower lip is exceedingly rare. This paper provides a comprehensive review of lower lip fibrolipoma cases treated at our hospital from 1982 to 2023 and examines relevant studies on labial lipoma from the CNKI and PubMed databases.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fibrolipoma of the lower lip: A case report and review of the literature

Wang,

Yu,

Gao

et al. 2024

Medicine

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Background: Fibrolipoma of the lower lip is an uncommon condition with limited documentation in the literature. This paper provides updated insights into oral and maxillofacial lipomas through a detailed case report and comprehensive literature review, discussing clinical features, pathogenesis, diagnostic approaches, histopathology, and therapeutic strategies. Case presentation: A 54-year-old female presented with a painless, enlarging mass on the inner aspect of her right lower lip, first noticed 2 years prior. The mass, now the size of a peanut, interfered with her eating and speech. Physical examination revealed a 2.0 × 2.5 × 1.0 cm mass beneath the mucous membrane of the right lower lip. It was firm, well-demarcated, and mobile. Surgical excision was performed, and histopathological analysis confirmed the diagnosis of a lower lip fibrolipoma. The lesion was successfully removed without recurrence. Conclusion: Lipomas in the oral and maxillofacial regions are rare, slow-growing benign tumors, particularly within the lips. Although their diagnosis is straightforward based on clinical presentation, histopathological confirmation is essential. Surgical resection remains the treatment of choice, with excellent prognostic outcomes.

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A rare case of oral melanoacanthoma

Cited by 5 publications

References 6 publications

Recent advances in managing and understanding seborrheic keratosis

Recent advances in managing and understanding seborrheic keratosis

Clinical Picture and Diagnostic Algorithm for the Management of Patients With Melanoacanthoma

Fibrolipoma of the lower lip: A case report and review of the literature

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