A rare case of Clostridium septicum aortitis with colon adenocarcinoma

Abstract

Clostridium septicum aortitis is a rare, highly morbid condition typically accompanied by malignant disease, such as hematologic cancer or colon adenocarcinoma. Presenting symptoms commonly described include acute onset of abdominal pain, nausea, and fevers. Prompt diagnosis of infectious aortitis is critical to prevent deadly complications, such as sepsis and vascular catastrophe. The described management largely involves surgical resection of the infected aorta, débridement, and arterial revascularization through extra-anatomic bypass or aortic graft placement.

Prospects of conservative treatment for Clostridium septicum–associated aortitis

“…Our literature search in August 2021 revealed a total of 72 cases of C. septicum –associated aortitis. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 Thus, the case we have presented is case number 73. Demographically, we found a predisposition for male sex (66.2%), older age (median, 76 years; interquartile range, 67-82 years), gastrointestinal malignancies (52.1%), and diabetes (22.5%).…”