A rare case of cellular angiofibroma affecting the periurethral region in a 38-year-old woman

Kumar, Pankaj; Singh, Smita; Kumar, Abhishek; Janoria, Somesh

doi:10.1136/bcr-2018-225386

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Patients with CAF typically present with a slow-growing painless mass, with a median duration of 5 months [ 1 ]. However, some individuals may experience mild-to-moderate pain or symptoms related to the surrounding tissues [ 1 , 11 - 12 ]. The median size of the tumor is 2.8 cm for women and 7 cm for men, and the cut surface typically appears gray-pink-brown [ 1 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

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Paratesticular Cellular Angiofibroma (CAF): A Rare Case Report

Gaspar Reis,

Alves,

Anacleto

et al. 2023

Cureus

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Cellular angiofibromas (CAFs) are infrequent and benign soft-tissue tumors that primarily affect the genitourinary region in both genders. The authors report the case of a 71-year-old male patient who exhibited progressively increasing swelling in both testicles, with greater prominence noted on the left side. Initial findings from physical examination and scrotal ultrasound indicated the possibility of bilateral hydrocele, so the patient was recommended surgical intervention of the left more prominent side. Intraoperatively, a left paratesticular mass was identified and subsequently excised. Histopathological analysis confirmed the diagnosis of cellular angiofibroma. Surgeons should be cognizant of this tumor type to optimize treatment strategies, as local excision demonstrates a potential to preserve the testicle and yield favorable outcomes. Although occurrences of local recurrence are extremely rare, long-term follow-up is imperative.

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Section: Discussionmentioning

confidence: 99%

“…However, some individuals may experience mild-to-moderate pain or symptoms related to the surrounding tissues [1,[11][12]. The median size of the tumor is 2.8 cm for women and 7 cm for men, and the cut surface typically appears gray-pink-brown [1,12].…”

Section: Discussionmentioning

confidence: 99%

Paratesticular Cellular Angiofibroma (CAF): A Rare Case Report

Gaspar Reis,

Alves,

Anacleto

et al. 2023

Cureus

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“…Surgical excision of the lesion with tumor-free margins seems to be the adequate management to these lesions. 9 It allows not only to treat the patient but also to achieve a correct diagnosis. The potential recurrence risk of these lesions is low, as there is only one case of recurrence reported in the literature, and no known malignant transformation.…”

Section: Discussionmentioning

confidence: 99%

Cellular Angiofibroma: A Rare Vulvar Tumor Case Report

Fachada

Pais

Fernandes

et al. 2020

Rev Bras Ginecol Obstet

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Cellular angiofibroma (CA)is a rare benign mesenchymal tumor. In women, it occurs mainly in the vulvovaginal region, with vulvar location in 70% of the cases. Its clinical presentation is nonspecific and similar to several other vulvar tumors of different cellular origins. Thus, its histological and immunohistochemical features allow distinction from other tumors. Cellular angiofibromas have good prognosis, despite some risk of relapse. The authors present the case of a 49-year-old woman with a bulky right vulvar lesion, for which the preoperative diagnosis was a Bartholin cyst, but the histological and immunohistochemical evaluation yielded a CA.

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Surgical excision of giant vulvar angiofibroma: A case report and a review of literature

et al. 2022

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Rationale: Cellular angiofibroma (CA) is a rare tumor of the soft tissue classified as a benign fibroblastic/myofibroblastic tumor. Considering this, the literature regarding CA mainly, but not exclusively, comprises single case reports and case series. Here, we report a case of giant CA of the vulva with comprehensive literature review.Patient concerns: We present a case of a massive vulvar CA arising in 53-year-old woman with no notable medical or surgical history. The mass has grown considerably over time, causing pain and difficult urination, defecation, and movement. The patient had normal regular menstrual cycle with no previous contraception use. Vaginal examination exposed a right-sided large tender vulvar mass with normal-looking vagina.Diagnoses: Pelvic magnetic resonance imaging with contrast revealed a large right vulvar heterogeneously enhancing soft tissue mass measuring 13.1 × 10.9 × 10.7 cm expending the left vulva, with internal and peripheral voids resembling feeding vessels. The mass was surgically removed, and subsequent histopathology showed skin-covered dermal-based lesion composed of fibroblast-like bland and spindle cell proliferation with thin-walled blood vessels of various sizes. Immunohistostaining of CD34 and smooth muscle antigen were both positive, while desmin was found to be negative. A diagnosis of vulvar angiofibroma was made based on the clinical scenario, imaging, and histopathology.Interventions: Mass vulvectomy was performed starting with a circumferential incision at the base of the mass and structural dissection to separate the mass from the vulvar wall. The incision was successfully closed, and subcuticular stitches were applied to the skin.Outcomes: The patient's complaints were significantly relieved with no postoperative complications and the patient is being followed regularly in an outpatient setting.Lessons: Due to its extremely benign nature of CA, and the implausible ability of its recurrence, it was decided to surgically excise it. Despite its rarity, it can be readily identified at its earlier stages preventing the vexing and exasperating symptoms accompanied with increased size as mentioned.

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A rare case of cellular angiofibroma affecting the periurethral region in a 38-year-old woman

Cited by 3 publications

References 11 publications

Paratesticular Cellular Angiofibroma (CAF): A Rare Case Report

Paratesticular Cellular Angiofibroma (CAF): A Rare Case Report

Cellular Angiofibroma: A Rare Vulvar Tumor Case Report

Surgical excision of giant vulvar angiofibroma: A case report and a review of literature

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