A rare case of a big left ventricular myxoma presenting with a cerebrovascular stroke

Mahmoud, Hamdy; Moursi, Ihab

doi:10.1016/j.ehj.2014.03.005

Cited by 9 publications

(10 citation statements)

References 10 publications

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“…Echocardiography was the first diagnostic modality, and further imaging was rarely required in our patients. 18F-fluorodeoxyglucose positron emission tomography/ computed tomography (FDG-PET/CT) has a sensitivity of over 90% in differentiating benign and malignant processes [8]. In our study, one case with a recurrent hemangioendothelioma required both FDG-PET/CT and CMR to assess the extent of recurrence and metastasis.…”

Section: Discussionmentioning

confidence: 90%

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Primary cardiac tumors: a spectrum of pathologies and scenarios

et al. 2020

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Background: Cardiac tumors are rare, and their diagnosis is challenging. The level of evidence for the management of cardiac tumors came from case reports or small case series. We aim to present our multicenter experience in the diagnosis and management of cardiac tumors. Results: We performed a prospective study, including 82 cases of cardiac tumors encountered at three centers in 5 years. The mean age was 62 ± 5.8 years old (range 2 months-74 years), and 91.4% were females constituted. The median EuroSCORE II was 4.27%. All cases underwent radical excision of the tumor. Five cases underwent additional mitral valve replacement and one case underwent coronary bypass grafting. Pathological diagnoses were left atrial myxomas (n = 65, 79.3%), right atrial myxomas (n = 5, 6.1%), bi-atrial myxomas (n = 2, 2.4%), right ventricular outflow tract myxoma (n = 1, 1.2%), myxosarcoma (n = 1, 1.2%), thymoma (n = 1, 1.2%), recurrent hemangioendothelioma (n = 1, 1.2%), round cell tumor (n = 1, 1.2%), cardiac lymphoma (n = 1, 1.2%), rhabdomyomas (n = 2, 2.4%), and renal cell carcinomas (n = 2, 2.4%). Two patients (2.4%) had re-exploration for bleeding. One patient (1.2%) with right atrial thymoma experienced a severe vasoplegia with unstable hemodynamics. Two patients had operative mortality (2.4%), one with recurrent cardiac hemangioendothelioma. During 1-year follow-up, one patient (1.2%) died because of metastatic myosarcoma. Recurrence was reported in 2 patients (2.4%). Conclusions: The clinical scenario of cardiac tumors depends mainly on tumor location and size rather than the histopathology. Surgical resection is feasible in benign tumors while very challenging in malignant tumors.

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Section: Discussionmentioning

confidence: 90%

“…According to previous reports, LV myxomas usually arise from the septal endocardium [10], and there are a few case reports of growth from the LV free wall [8,11]. Cardiac myxomas related to the Carney complex (CNC) more frequently occur in the left ventricle, compared with sporadic myxomas [11].…”

Section: Discussionmentioning

confidence: 99%

Primary cardiac tumors: a spectrum of pathologies and scenarios

et al. 2020

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“…The long list of reported symptoms and signs includes chest pain, dyspnea, orthopnea, fever, malaise and fatigue, weight loss, pancreatitis [9], cough, palpitation, cyanosis and clubbing, Raynaud's phenomenon, arthralgia, myalgia, muscle weakness, loss of hair, dizziness, fainting, aphasia, peripheral embolism [16], syncope, transient ischemic attack (TIA), cerebrovascular accident (CVA) [10–12, 17], sudden cardiac death [5, 12, 18], and heart failure [19]. These symptoms may accompany the change in body position.…”

Section: Discussionmentioning

confidence: 99%

A Large Left Ventricle Myxoma: Presenting with Epigastric Pain and Weight Loss

Fakhari

Bilehjani

2016

Case Reports in Cardiology

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Cardiac myxomas are the most common benign tumors found in the heart. They usually appear in the left atrium. Those originating from the left ventricle (LV) are rare. Although clinical presentation may vary, dyspnea and embolism are the most commonly reported symptoms. In the present case study, a 27-year-old woman with a large myxoma originating from the left ventricular free wall is studied. She had atypical complaints, mainly epigastric discomfort, nausea, vomiting, and anorexia. She was hospitalized for acute abdomen, but subsequent investigations revealed a large myxoma that fully filled the LV and severely compromised the flow of the aortic and mitral valves. After successful emergency tumor resection, all symptoms disappeared. The uncommon presentation caused by these tumors is discussed in this study.

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“…d) Echocardiography Two-dimensional echocardiography is the diagnostic procedure of choice in revealing myxomas [26]. A big (2.5 × 5 cm) grape-like mass in the left ventricle suggestive of myxoma, attached to the inferior septum and bulging into the left ventricular outflow tract had been described by a routine Transthoracic echocardiography in a 35 year old Asian male [27]. A large left ventricular myxoma, a pedunculated pear-shaped mass (75 × 45 mm in diameter), attached by a pedicle to the apical interventricular septum and prolapsing through the LV outflow tract and aortic valve , causing a severe obstruction was found by echocardiography in a 60 year old woman [28].…”

Section: Discussionmentioning

confidence: 99%

Left Ventricular Myxoma—A Case Report

Muthiah¹

2016

CRCM

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Left ventricular myxomas are extremely rare and account for 2.5% of all cardiac myxoma cases. A left ventricular myxoma originating from the apical interventricular septum and projecting into the left ventricular cavity was diagnosed by Transthoracic two-dimensional echocardiographic imaging in a 29-year-old male. The presentation of myxoma with symptoms masquerading as infectious hepatitis and dilated cardiomyopathy with a measured ejection fraction of 20% has been described.

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A rare case of a big left ventricular myxoma presenting with a cerebrovascular stroke

Cited by 9 publications

References 10 publications

Primary cardiac tumors: a spectrum of pathologies and scenarios

Primary cardiac tumors: a spectrum of pathologies and scenarios

A Large Left Ventricle Myxoma: Presenting with Epigastric Pain and Weight Loss

Left Ventricular Myxoma—A Case Report

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