Abstract:99Tcm-tetrofosmin (Myoview, Amersham Healthcare) is widely used as a radiopharmaceutical for myocardial perfusion imaging. Control of its radiochemical purity after reconstitution is usually performed by means of ITLC-SG paper chromatography in a mobile phase of methylene chloride/acetone (65/35), as recommended by the manufacturer. The present study describes the application of tetrahydrofuran in phosphate buffer for the development of 99Tcm-tetrofosmin on ITLC-SG strips. The use of this mobile phase signific… Show more
“…Since the HPLC system in use has been especially designed for the quantification of weak β-emitters like 3 H and 14 C, we first assess the behavior of 99m Tc in a liquid scintillation detection system. Under conditions of low-quenching (i.e.…”
Section: Hplc Analysis and Stability Of 99m Tc-mag-3mentioning
“…Since the HPLC system in use has been especially designed for the quantification of weak β-emitters like 3 H and 14 C, we first assess the behavior of 99m Tc in a liquid scintillation detection system. Under conditions of low-quenching (i.e.…”
Section: Hplc Analysis and Stability Of 99m Tc-mag-3mentioning
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