A Rapid and Highly Selective Resonance Scattering Spectral Assay for Trace Carcinoembryonic Antigen

Li, Jianfu; Jiang, Zhiliang; Deng, Anping

doi:10.1002/cjoc.200890407

Cited by 6 publications

(4 citation statements)

References 30 publications

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“…Recently, the resonance scattering (RS) spectral method has been widely used in monitoring trace metal ions and some other organic/inorganic molecules, such as antigens, melamine, protein, and DNA, − because of its simplicity, rapidity, sensitivity, and low cost . Tao and his co-workers revealed that the RS technique combined with an inorganic catalyst can amplify the response signals, which can significantly enhance the sensitivity and selectivity of the method .…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive Resonance Scattering (RS) Spectral Detection for Trace Tetracycline in Milk Using Aptamer-Coated Nanogold (ACNG) as a Catalyst

Luo

Zhan

et al. 2014

J. Agric. Food Chem.

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This paper reports an ultrasensitive resonance scattering (RS) method to detect tetracycline (TET) in milk based on the competition of aptamers between nanogold and TET, aggregation of naked nanogold, nanocatalytic Fehling reaction, and RS signals of catalytic product Cu₂O cubic. The detection principle was confirmed by the nanoparticle size analyzer (NANOS), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The variations of RS intensity had good linear correlation with TET concentrations, and the limit of detection was calculated as 11.6 nM. The proposed method was successfully applied for analysis of TET in milk, with total recoveries ranging from 105 to 109%.

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Section: Introductionmentioning

confidence: 99%

Ultrasensitive Resonance Scattering (RS) Spectral Detection for Trace Tetracycline in Milk Using Aptamer-Coated Nanogold (ACNG) as a Catalyst

Luo

Zhan

et al. 2014

J. Agric. Food Chem.

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“…[15][16][17][18][19][20] Recently, some immunoreaction, nanogold labeled immunoreaction and immunonanogold catalytic reaction have been utilized to establish some new RS methods for detection of antigen and haptene. [21][22][23][24] In addition, the combining RS technique with inorganic catalytic reaction and enzyme catalytic reaction was applied to analysis of trace inorganic ion, organic compound and enzyme activity. For example, using the enzyme catalytic effect, an enzyme catalytic-RS method for lysozyme activity was established.…”

Section: Introductionmentioning

confidence: 99%

A New and Sensitive Catalytic Resonance Scattering Spectral Assay for the Detection of Laccase Activity Using H2O2-I−-TDMAC System

2011

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In pH 3.8 acetic acid-sodium acetate (HAC-NaAC) buffer solution, laccase exhibited a strong catalytic effect on the H 2 O 2 oxidation of I -to form I 2 , and I 2 combined with excess I -to form 3 I -that reacted with cationic surfactants of tetradecyl dimethylbenzyl ammonium chloride (TDMAC) to produce the (TDMAC-I 3 ) n association complex particles, which exhibited a strong resonance scattering (RS) peak at 468 nm. Under the chosen conditions, as the concentration of laccase activity increased, the RS intensity at 468 nm (I 468 nm ) increased linearly. The increased RS intensity ∆I 468 nm was linear to laccase activity in the range of 0.08-0.96 U/mL, with a regression equation of ∆I 468 nm ＝88.8U-1.9, and a detection limit of 0.02 U/mL laccase. This proposed method was applied to detect laccase activity in waste water, with satisfactory results.

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“…Our group has used protein and aptamer to modify AuNPs, based on their good biocompatibility. Combined with the RS effect of AuNPs, we have established immunoanalysis 24,25 and aptamer analysis 26,27 to detect specific targets. Furthermore, we have improved the sensitivity by integrating aptamer analysis with AuNP-catalysis.…”

Section: Introductionmentioning

confidence: 99%

Resonance scattering spectral detection of trace ATP based on label-free aptamer reaction and nanogold catalysis

Liang

Ouyang

Jiang

2011

Analyst

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Double-stranded DNA (dsDNA) cannot protect gold nanoparticles (AuNPs) in the presence of NaCl, and dsDNA interacted with adenosine triphosphate (ATP) to form stable G-quartet and a single-stranded DNA (DNA 2) that can protect AuNPs. The unprotected AuNPs were aggregated to AuNP aggregations (AuNPA) that exhibited a resonance scattering (RS) peak at 590 nm. The RS intensity at 590 nm decreased linearly when the ATP concentration increased in the range of 6.6-110 nM. The catalysis of AuNP-DNA 2 was stronger than that of the AuNPA on the glucose-Cu(II) particle reaction, and the product appeared as an RS peak at 620 nm. When the ATP concentration was increased, the AuNP-DNA 2 increased, and the RS intensity at 620 nm increased linearly. The increased RS intensity (ΔI(620 nm)) was linear to ATP concentration in the range of 2.2-220 nM, with a regression equation of ΔI(620 nm) = 0.709C + 7.7, and a detection limit of 0.5 nM. Hereby, a new RS method of ATP detection was set up with high sensitivity and selectivity.

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A Rapid and Highly Selective Resonance Scattering Spectral Assay for Trace Carcinoembryonic Antigen

Cited by 6 publications

References 30 publications

Ultrasensitive Resonance Scattering (RS) Spectral Detection for Trace Tetracycline in Milk Using Aptamer-Coated Nanogold (ACNG) as a Catalyst

Ultrasensitive Resonance Scattering (RS) Spectral Detection for Trace Tetracycline in Milk Using Aptamer-Coated Nanogold (ACNG) as a Catalyst

A New and Sensitive Catalytic Resonance Scattering Spectral Assay for the Detection of Laccase Activity Using H2O2-I−-TDMAC System

Resonance scattering spectral detection of trace ATP based on label-free aptamer reaction and nanogold catalysis

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