A randomized prospective trial comparing the levonorgestrel-releasing intrauterine system with thermal balloon ablation for the treatment of heavy menstrual bleeding

Souza, Sérgio S. de; Camargos, Aroldo F.; Rezende, Cristiana Perdigão; Pereira, Francisco de Assis Nunes; Araújo, Cícero Augusto Alves; Filho, Agnaldo Lopes Silva

doi:10.1016/j.contraception.2009.09.012

Cited by 30 publications

(10 citation statements)

References 15 publications

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“…It does not, however, reduce the duration of menses or regulate the menstrual cycle 15 . It is speculated that tranexamic acid use may contribute to an increased risk of venous thromboembolism, although Sundstrom et al 36 recently reported that this medication does not significantly increase this risk (adjusted odds ratio 3.20; 95% CI, 0.65‐15.78). More research is needed to confirm this finding.…”

Section: Managementmentioning

confidence: 99%

“…It is an attractive option, especially for younger women, because it is cost-effective, reversible, and fertility preserving. 37 Moreover, up to 97% of women report no restrictions in their activities of daily living after 1 year of LNG-IUS treatment. 38 The LNG-IUS also is demonstrably effective for approximately 70% of properly selected obese women.…”

Section: Pharmacologic Treatmentsmentioning

confidence: 99%

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Abnormal Uterine Bleeding During the Reproductive Years

Davidson

DiPiero²,

Govoni³

et al. 2012

J Midwife Womens Health

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Abnormal uterine bleeding is one of the most common reasons that reproductive-aged women seek health care. The causes are varied, depending in large part on the age and life stage of the woman. Thus, diagnosis requires a systematic approach that is driven by a thorough health history and review of presenting symptoms. In recent years, the treatment of abnormal uterine bleeding has moved away from surgical procedures in favor of more conservative, yet effective, hormonal therapy such as combined contraceptives and the levonorgestrel-releasing intrauterine system. Clinicians must be knowledgeable about the various abnormal uterine bleeding treatment options and partner with women to develop appropriate, individualized treatment plans. The purpose of this article is to synthesize the current literature to describe the contributing etiologies, common presentations, diagnosis, evaluation, and management of abnormal uterine bleeding.

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Section: Managementmentioning

confidence: 99%

Section: Pharmacologic Treatmentsmentioning

confidence: 99%

Abnormal Uterine Bleeding During the Reproductive Years

Davidson

DiPiero²,

Govoni³

et al. 2012

J Midwife Womens Health

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“…). One study did not include data of interest and six compared thermal balloon ablation with other surgical techniques. Therefore, six studies, involving 901 patients, were included in the present meta‐analysis.…”

Section: Resultsmentioning

confidence: 99%

Meta‐analysis of bipolar radiofrequency endometrial ablation versus thermal balloon endometrial ablation for the treatment of heavy menstrual bleeding

Zhai

Zhang

Wang

et al. 2017

Intl J Gynecology & Obste

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“…Both treatment modalities were associated with similar reductions in menstrual blood loss and similar improvements in health‐related quality of life for up to two years. Subsequently, one RCT showed greater reduction of pictorial blood loss assessment chart scores in LNG‐IUS users, compared to endometrial ablation at one‐year follow‐up (72). In addition, a further systematic review and meta‐analysis, including data from individual patients (73) was recently published, using patient dissatisfaction rates as the primary efficacy measure.…”

Section: Resultsmentioning

confidence: 99%

Recent developments in the clinical use of the levonorgestrel‐releasing intrauterine system

Gemzell‐Danielsson

Inki

Heikinheimo

2011

Acta Obstet Gynecol Scand

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This overview focuses on recent developments in the clinical use of the levonorgestrel- releasing intrauterine system (LNG-IUS) on established indications. Recent studies confirm that the LNG-IUS is safe and equally effective for all age groups of women. All available studies showed that intrauterine contraception is more effective when compared to non-intrauterine contraceptive methods to prevent repeat abortions. Furthermore, insertion in young nulliparous women is acceptable in the majority of women and associated with high continuation rates. The effectivity of LNG-IUS appears to be similar in women with chronic medical conditions, including HIV infection or coagulation disorders, and healthy women. More and most importantly, it has no adverse effect on the underlying condition. We also discuss effects of LNG-IUS on bone mineral density, vaginal flora, cardiovascular risk factors and breast cancer. In treatment of heavy menstrual bleeding, the LNG-IUS appears to be one of the most effective and cost-effective methods.

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A randomized prospective trial comparing the levonorgestrel-releasing intrauterine system with thermal balloon ablation for the treatment of heavy menstrual bleeding

Cited by 30 publications

References 15 publications

Abnormal Uterine Bleeding During the Reproductive Years

Abnormal Uterine Bleeding During the Reproductive Years

Meta‐analysis of bipolar radiofrequency endometrial ablation versus thermal balloon endometrial ablation for the treatment of heavy menstrual bleeding

Recent developments in the clinical use of the levonorgestrel‐releasing intrauterine system

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