A Randomized Controlled Trial to Examine the Posttreatment Efficacy of Neurofeedback, Behavior Therapy, and Pharmacology on ADHD Measures

Moreno-García, Inmaculada; Meneres-Sancho, Susana; Rey, Carlos Camacho-Vara de; Servera, Mateu

doi:10.1177/1087054717693371

Cited by 28 publications

(23 citation statements)

References 27 publications

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“…The other analyses using data from stimulant treatment groups were less conclusive. The results calculated using probably blinded measures and pre–post differences had high heterogeneity if Moreno-García, Meneres-Sancho, Camacho-Vara de Rey, and Servera’s (2019) data were included. When this study was eliminated from the analyses, significant heterogeneity disappeared and significant effect sizes in favor of stimulant treatment were obtained, but only four and three studies were incorporated in the analyses (inattention and hyperactivity/impulsivity, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…With regard to neurofeedback groups versus stimulant treatment group results, in recent years, new RCTs have appeared that allowed us to compare the effects of these treatments (a total of six studies in our analyses, see Table 2), including four studies in 2017-2018 (Duric, Assmus, Gundersen, Duric-Golos, & Elgen, 2017; Geladé et al, 2018; Moreno-García et al, 2019; Sudnawa et al, 2018). Until now, to the authors’ knowledge, no meta-analysis had been able to include the minimum number of these conditions in studies to report some conclusion.…”

Section: Discussionmentioning

confidence: 99%

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What Do Meta-Analyses Have to Say About the Efficacy of Neurofeedback Applied to Children With ADHD? Review of Previous Meta-Analyses and a New Meta-Analysis

et al. 2019

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Objective: We reviewed previously published meta-analyses of neurofeedback applied to children with ADHD and conducted a new meta-analysis of randomized controlled trials (RCTs) that updates previous results and incorporates methodological modifications. Method: Searches were carried out through PubMed, Sage, PsycINFO, SpringerLink, and Psicodoc. We used Hedges’ (adjusted) g and a random-effects model. To assess heterogeneity, Q and I2 were calculated. We performed different analyses depending on the control groups, ADHD symptoms, pre- and/or posttreament data used and symptom evaluator. Results: We reviewed seven meta-analyses, and 17 studies were incorporated into the meta-analysis. RCTs support the efficacy of neurofeedback applied to ADHD when most proximal evaluators assess symptoms. Neurofeedback significantly improves inattention symptoms when possibly blinded evaluators assess symptoms. The preliminary results suggest that stimulant medication is more effective than neurofeedback. Conclusion: New RCTs that establish links between ADHD symptom measurements, subjects’ learning after neurofeedback, and neurophysiological measures could improve the quality of the conclusions.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

What Do Meta-Analyses Have to Say About the Efficacy of Neurofeedback Applied to Children With ADHD? Review of Previous Meta-Analyses and a New Meta-Analysis

et al. 2019

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“…The Neurofeedback-based therapy in ADHD treatment is still a controversial method compared to pharmacological or behavioral ones; however, it is becoming more and more popular due to the increasing number of publications describing its positive results (Bluschke et al, 2016;Moreno-Garcia et al, 2015;Moreno-Garcia et al, 2019). The vast body of literature in the Neurofeedback field suggests that specific bandwidths are associated with particular cognitive functions.…”

Section: Methodsmentioning

confidence: 99%

Initial Study on Implementation of the Low-Frequency Wave Markers for the Purpose of Diagnostic Tests’ Performance and Neurofeedback Therapy

Zolubak

Pelc

Ožana

et al. 2019

Studies in Logic, Grammar and Rhetoric

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The paper focuses on automation of signal processing, which also considers analysis of biomedical data, such as EEG. The results of the study prove that this enables a better understanding of signal changes and makes it possible to address some specific disturbances. It also makes it possible to describe the relevant changes in signals mathematically and helps to create markers of various brain disorders. This paper presents the study at the initial stage and focuses on the mathematical markers of concentration disorders associated with Theta waves. The presented markers presented are based on Welch’s periodograms. The obtained results are very promising and further studies aimed at refining them are currently being carried out.

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“…Secondary outcomes will be the number of dropouts for any reasons at the end of the intervention (and, if available, at follow-up) and neuropsychological laboratory-based measures of working memory (e.g., The visual spatial working memory task, [ 38 ] attention (e.g., Test of Variables of Attention, [ 39 , 40 ] Attention Endurance Test (d2) [ 41 ] ), and inhibition (e.g., Integrated Visual and Auditory Continuous Performance Test). [ 42 ]…”

Section: Methodsmentioning

confidence: 99%

Effects of neurofeedback versus methylphenidate for the treatment of attention-deficit/hyperactivity disorder protocol for a systematic review and meta-analysis of head-to-head trials

Yan

Zhang

Yuan³

et al. 2018

Medicine

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Introduction:Attention-deficit/hyperactivity disorder (ADHD) is developmental disorder characterized by inattention and/or hyperactivity/impulsivity. Psychostimulants, including methylphenidate (MPH), are recommended as a first-line pharmacological intervention, whereas neurofeedback (NF) has been proposed as a nonpharmacological option. The comparative effects of MPH and NF need further exploration. We will conduct a systematic review and meta-analysis of head-to-head randomized controlled trials (RCTs) comparing the efficacy and/or tolerability of MPH and NF in children/adolescents and adults with ADHD.Method and Analysis:We will include published as well as unpublished data. Two investigators will independently search PubMed, OVID, ERIC, Web of Science, ClinialTrials.gov, and a set of Chinese databases, including CNKI, CQVIP, and WanFang for head-to-head RCTs comparing MPH and NF. Experts will be contacted for unpublished data. The primary outcome will be the efficacy on ADHD core symptoms, measured by the change in the severity of ADHD symptoms, from baseline to endpoint and, if available, at follow-up (at any available time point). Secondary outcomes will be: dropouts for any reasons; efficacy on neuropsychological measures (working memory, inattention, and inhibition). We will conduct subgroup analyses to assess the impact of the following variables: age; type of NF; language of publication; comorbidities. Additionally, we will carry out meta-regression analyses to investigate the effect of sponsorship, year of publication, duration of intervention, and age of participants. Sensitivity analyses will be conducted to test the robustness of the findings. Risk of bias of individual studies will be assessed using the Cochrane risk of bias tool. Analyses will be performed using Comprehensive Meta-Analysis Software.Ethics and Dissemination:No ethical issues are foreseen. Results from this study will be published in a peer-reviewed journal and presented at relevant national and international conferences.Trials registration number:PROSPERO CRD42018090256.

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A Randomized Controlled Trial to Examine the Posttreatment Efficacy of Neurofeedback, Behavior Therapy, and Pharmacology on ADHD Measures

Abstract: From a global perspective, behavior therapy had the most extensive results, but PH had the greatest capacity to improve overall attention. NF was able to improve both control response and inattention. Clinical implications are discussed.

Cited by 28 publications

References 27 publications

What Do Meta-Analyses Have to Say About the Efficacy of Neurofeedback Applied to Children With ADHD? Review of Previous Meta-Analyses and a New Meta-Analysis

What Do Meta-Analyses Have to Say About the Efficacy of Neurofeedback Applied to Children With ADHD? Review of Previous Meta-Analyses and a New Meta-Analysis

Initial Study on Implementation of the Low-Frequency Wave Markers for the Purpose of Diagnostic Tests’ Performance and Neurofeedback Therapy

Effects of neurofeedback versus methylphenidate for the treatment of attention-deficit/hyperactivity disorder protocol for a systematic review and meta-analysis of head-to-head trials

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