A Randomized Controlled Trial of Silver Sulfadiazine, Biafine, and Saline-soaked Gauze in the Treatment of Superficial Partial-thickness Burn Wounds in Pigs

Canine acute radiation dermatitis, a survey of current management practices in North America

“… 14 SSD has been shown to decrease bacterial colonization in burn wounds; however, there is no definitive evidence of decreased infection rates or healing time 15,16 . A study evaluating healing times in partial thickness burn wounds in pigs found no difference between SSD, Biafine and saline‐soaked gauze 17 . Although the pathophysiology of chemical, thermal and ultraviolet radiation induced burns is distinct from that of acute radiation dermatitis, there is a risk of bacterial infection in all cases because of compromised skin barrier function 18 .…”

Effect of Honey on Healing ofPseudomonas aeruginosaInfected Burn Wounds in Rat

“…11.324.9 d, P=0.015; Hauser et al, 2007). The benefit of a moist wound environment and reepithelialization has been shown previously (Westerhof et al, 2001;Glesinger et al, 2004).…”

Silver sulfadiazine for the treatment of partial-thickness burns and venous stasis ulcers

“…Epithelialization rates were improved with SSD treatment in murine and rat models, [8][9][10] as opposed to swine studies, which failed to show improved reepithelialization rates. 11,12 Wound contracture rates and healing times have similarly shown improvement in murine and rat models but have not been assessed in swine. 8,10,13 Infection rates were not improved in swine models, 11,12 and mortality has been reported with inconsistent results in rat studies.…”

“…11,12 Wound contracture rates and healing times have similarly shown improvement in murine and rat models but have not been assessed in swine. 8,10,13 Infection rates were not improved in swine models, 11,12 and mortality has been reported with inconsistent results in rat studies. 9,14 Of note, there is a noticeable paucity of randomized controlled trials, with most of the aforementioned studies published only after the institution of SSD as standard therapy.…”