A Randomized Controlled Trial of Superior and Inferior Temporomandibular Joint Space Injection With Hyaluronic Acid in Treatment of Anterior Disc Displacement Without Reduction

Osteoarthritic Changes After Superior and Inferior Joint Space Injection of Hyaluronic Acid for the Treatment of Temporomandibular Joint Osteoarthritis With Anterior Disc Displacement Without Reduction: A Cone-Beam Computed Tomographic Evaluation

“…1 to evaluate osteoarthritic changes in TMJ by CBCT. [9][10][11] Previously, we reported a method to treat disc displacement without reduction of TMJ by superior and inferior joint space injection with HA 8 . The purpose of this study was to observe the TMJ condylar bony changes and the joint function after HA superior and inferior joint space injection by CBCT.…”

“…The injection method was described as before. 8 The entry point of the needle was about 10 mm anterior to the tragus. In superior joint space injection, patients were asked to open mouth widely; the tip of the needle was then directed to the glenoid fossa anteriorly, superiorly, and medially.…”

Preliminary evaluation of histological changes found in a mechanical arthropatic temporomandibular joint (TMJ) exposed to an intra-articular Hyaluronic acid (HA) injection, in a rat model

“…The lubricating and anti-inflammatory effects of the synovial fluid help to reduce TMJ pain (Long et al, 2009).…”

Stem Cells for Temporomandibular Joint Repair and Regeneration

“…Often, these pharmacological therapies remain insufficient to alleviate pain and are associated with persisting safety and tolerability issues. Minimallyinvasive modalities have also been advocated and comprised of intra-articular injections of chondroprotective agents such as hyaluronic acid (HA) [17], glucosamine [12] and corticosteroids [2] into the superior joint space (Fig. 1).…”