A randomized controlled trial comparing water exchange and air insufflation during colonoscopy without sedation

Abstract

WE is superior to AI for attenuating insertion pain during colonoscopy without sedation, but its efficacy is limited in more painful endoscopy.

Bayesian network meta‐analysis: Efficacy of air insufflation, CO2 insufflation, water exchange, and water immersion in colonoscopy

“…Adenoma detection rate was described in 16 studies. 17,18,23,24,27,31,33,34,38,40,41,45,46,49,52,55 We observed that air insufflation (OR = 0.71, 95% CrI: 0.6-0.83, Table 3), CO 2 insufflation (OR = 0.75, 95% CrI: 0.56-0.99, Table 3) and water immersion (OR = 0.77, 95% CrI: 0.62-0.96, Table 3) had a significantly lower adenoma detection rate than water exchange.…”

“…Forty RCT with 13 734 patients were included from 1060 articles searched through databases and other sources (Fig. ).…”

“…Twenty‐three studies focused on the analysis regarding cecal intubation time. According to our analysis, we did not get any significant results on cecal intubation time.…”

“…Twenty-three studies 18,[20][21][22][24][25][26]28,[30][31][32][33]35,[38][39][40]43,45,49,51,52,54,55 focused on the analysis regarding cecal intubation time. According to our analysis, we did not get any significant results on cecal intubation time.…”

Water exchange colonoscopy increases adenoma detection rate: a systematic review with network meta-analysis of randomized controlled studies

“…Our search identified 155 publications. Seventeen RCTs [2][3][4][5][6][9][10][11][17][18][19][20][21][33][34][35][36] were included in the analysis (41 arms of treatment, 10,350 patients; 55.7% male patients; Supplementary Figs. 1 and 2, available online at www.…”