A randomized, controlled clinical trial on the clinical, microbiological, and staining effects of a novel 0.05% chlorhexidine/herbal extract and a 0.1% chlorhexidine mouthrinse adjunct to periodontal surgery

Abstract

The test CHX rinse resulted in less tooth staining. At the study endpoint, similar and high counts of periodontal pathogens were found.

Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review

“…, Duss et al. ). The efficacy of low CHX concentrations on the reduction on gingival inflammation however remains unclear.…”

The long‐term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra‐oral halitosis—A randomized clinical trial

“…Tooth staining has been reported as a common adverse event in subjects using 0.12 per cent chlorhexidine mouth rinse (McCoy et al., ). Using a lower concentration of CHX results in less tooth staining (Duss, Lang, Cosyn, & Persson, ). The mouth rinse used in the present study only contained 0.025% chlorhexidine diacetate.…”

Effect of non surgical periodontal treatment on TNF-α levels in serum of patients with chronic periodontitis

“…Our results were in the same direction with Chauhan et al, 18 who observed that a significant reduction in (PPD) and gain in (CAL) between base line and three months follow up (P <0.05). In a randomized, control clinical trial, 19 In contrast to our findings a systematic review on the effects of local antimicrobials as adjuncts to subgingival debridement, compared with subgingival debridement alone, in the treatment of chronic periodontitis demonstrated that the application of CHX and metronidazole showed a minimal effect when compared with placebo on BOP, CAL and PPD. 20 A systematic review of the effect of full mouth debridment with and without antiseptics in patients with chronic periodontitis by Lang et al, 21 reported that despite the significant differences of modest magnitude, full mouth debridement with antiseptic or full mouth scaling and root planning without antiseptic don't provide clinically relevant advantages over conventional staged debridement in BOP, CAL and PPD.…”