A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda

Wawer, Maria J.; Gray, Ronald H.; Sewankambo, Nelson; Serwadda, David; Paxton, Lynn A.; Berkley, Seth; McNairn, Denise; Wâbwire-Mângen, Fred; Li, Chuanjun; Nalugoda, Fred; Kiwanuka, Noah; Lutalo, Thomas; Brookmeyer, Ronald; Kelly, Robert J.; Quinn, Thomas C.

doi:10.1097/00002030-199810000-00014

Cited by 201 publications

(137 citation statements)

References 47 publications

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“…Participants are from the ongoing Rakai Community Cohort Study described in detail elsewhere (26). Briefly, the Rakai Community Cohort Study conducts annual home-based surveys, with comprehensive interviewer-administered questionnaires on sociodemographic, behavioral, and health characteristics, on an average population of 12,000 adults ages 15 to 49 years.…”

Section: Methodsmentioning

confidence: 99%

Determinants of Incidence and Clearance of High-Risk Human Papillomavirus Infections in Rural Rakai, Uganda

Safaeian¹,

Kiddugavu

Gravitt³

et al. 2008

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Background: We used self-administered vaginal swabs to assess the incidence and clearance of carcinogenic human papillomavirus (HPV) infections in rural Rakai, Uganda. Methods: Women provided self-administered vaginal swab at annual home-based visits. Type-specific carcinogenic HPV incidence and clearance and risk factors were assessed. Results: Carcinogenic HPV incidence was 17.3 per 100 person-years among HIV-positive women compared with 7.0 per 100 person-years among HIV-negative women (P < 0.001). HPV-51 had the highest incidence followed by HPV-16 (1.8 per 100 and 1.5 per 100 personyears, respectively). In multivariate model, HIV-positive women were twice as likely to have incident infection compared with HIV-negative women. Younger women were at higher risk for incident infection,

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Section: Methodsmentioning

confidence: 99%

Determinants of Incidence and Clearance of High-Risk Human Papillomavirus Infections in Rural Rakai, Uganda

Safaeian¹,

Kiddugavu

Gravitt³

et al. 2008

Cancer Epidemiology, Biomarkers &Amp; Prevention

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“…[1][2][3][4][5][6] In Africa, the reported prevalence of syphilis in pregnancy ranges from 3.6% to 19%. [7][8][9][10][11][12][13] Although syphilis screening in pregnancy is a national health policy in most African countries, few screening programs achieve implementation, mainly owing to financial and logistical constraints.…”

mentioning

confidence: 99%

Syphilis control during pregnancy: effectiveness and sustainability of a decentralized program

Fonck

Claeys²,

Farah³

et al. 2001

Am J Public Health

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OBJECTIVES: This study sought to assess the performance, effectiveness, and costs of a decentralized antenatal syphilis screening program in Nairobi, Kenya. METHODS: Health clinic data, quality control data, and costs were analyzed. RESULTS: The rapid plasma reagin (RPR) seroprevalence was 3.4%. In terms of screening, treatment, and partner notification, the program's performance was adequate. The program's effectiveness was problematic because of false-negative and false-positive RPR results. The cost per averted case was calculated to be US$95 to US$112. CONCLUSIONS: The sustainability of this labor-intensive program is threatened by costs and logistic constraints. Alternative strategies, such as the mass epidemiologic treatment of pregnant women in high-prevalence areas, should be considered.

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“…The data collection was conducted with community members who are part of the Rakai Health Sciences Program (RHSP) and its longitudinal epidemiological surveillance cohort. The cohort includes 15-49 year olds selected from 33 communities within the Rakai district interviewed in surveys conducted every 12-20 months [24]. In the cohort, the average age of the respondents is 28 years for men and 27 years for women.…”

Section: Study Sitementioning

confidence: 99%

Re-focusing HIV Prevention Messages: A Qualitative Study in Rural Uganda

Mathur

Romo

Rasmussen

et al. 2016

Journal of Adolescent Health

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A randomized, community trial of intensive sexually transmitted disease control for AIDS prevention, Rakai, Uganda

Abstract: Testing the effects of STD control on AIDS prevention is feasible in this Ugandan setting.

Cited by 201 publications

References 47 publications

Determinants of Incidence and Clearance of High-Risk Human Papillomavirus Infections in Rural Rakai, Uganda

Determinants of Incidence and Clearance of High-Risk Human Papillomavirus Infections in Rural Rakai, Uganda

Syphilis control during pregnancy: effectiveness and sustainability of a decentralized program

Re-focusing HIV Prevention Messages: A Qualitative Study in Rural Uganda

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