A randomized clinical trial of high volume peritoneal dialysis versus extended daily hemodialysis for acute kidney injury patients

Ponce, Daniela; Berbel, Marina Nogueira; Abrão, Juliana Maria Gera; Góes, Cassiana Regina de; Balbi, André Luís

doi:10.1007/s11255-012-0301-2

Cited by 76 publications

(83 citation statements)

References 30 publications

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“…In another prospective study comparing the effect of HVPD and prolonged HD (PHD) on AKI patients' outcome, 51 the PHD and HVPD groups were similar in sex, disease severity scores, and etiology of AKI. There was a trend toward statistical difference regarding the presence of sepsis (62.3% in the PHD group vs 44.9% in the HVPD group, P=0.054).…”

Section: Pd Outcomes In Akimentioning

confidence: 99%

Acute kidney injury: risk factors and management challenges in developing countries

Ponce¹,

Balbi²

2016

IJNRD

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Acute kidney injury (AKI) is a major global health problem in both developed and developing nations, negatively affecting patient morbidity and responsible for an estimated 1.4 million deaths per year. Although the International Society of Nephrology set a goal of eliminating preventable deaths from AKI by 2025, implementation of this program in developing countries presents major challenges not only because of the lack of resources but also because of the scarce data addressing the epidemiology and causes of AKI in developing countries, the limited health care resources to diagnose and treat AKI, and the poor awareness of the impact of AKI on patient outcomes.

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Section: Pd Outcomes In Akimentioning

confidence: 99%

Acute kidney injury: risk factors and management challenges in developing countries

Ponce¹,

Balbi²

2016

IJNRD

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“…Ponce et al [17], performed a trial to assess dosing patterns of PD in critically ill AKI patients, randomized to receive higher or lower intensity PD therapy (prescribed weekly Kt/V of 5.6 vs. 3.5). The 2 groups had similar mortality rates after 30 days (55 vs. 53%, p = 0.83).…”

Section: Pd Adequacy In Akimentioning

confidence: 99%

“…The same Brazilian group performed another prospective study comparing the effect of HVPD and prolonged HD (PHD) on AKI patients' outcome [20]. Delivered Kt/V and ultrafiltration were higher in the PHD group; however, there was no difference between the 2 groups in mortality and recovery of kidney function or need for chronic dialysis.…”

Section: Pd Outcomes In Akimentioning

confidence: 99%

Peritoneal Dialysis Treatment Modality Option in Acute Kidney Injury

Ponce

Gobo-Oliveira

Balbi³

2017

Blood Purif

122

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Background: Peritoneal dialysis (PD) may be a feasible and safe alternative to haemodialysis not only in the chronic but also in the acute setting. It was previously widely accepted as a modality for acute kidney injury (AKI) treatment, but its practice declined in favor of other types of extracorporeal therapies. Summary: The interest in PD to manage AKI patients has been increased and PD is now frequently used in developing countries because of its lower cost and minimal infrastructural requirements. Studies from these countries have shown that, with careful thought and planning, critically ill patients can be successfully treated using PD. Some of the classic limitations of PD use in AKI, such as infectious and mechanical complications and poor metabolic control, have been decreased with the use of cyclers, flexible catheters, and a high volume of dialysate. The recent publication of the International Society of Peritoneal Dialysis guidelines for PD in AKI has tried to address these issues and provide an evidence-based standard by which to initiate therapy. Key Message: In this review, advances in technical aspects and the advantages and limitations of PD were discussed; it clearly showed that PD is a simple, safe, and efficient way to correct metabolic, electrolyte, acid - base, and volume disturbances generated by AKI and it can be used as a renal replacement therapy modality to treat AKI, both in and out of the intensive care unit setting.

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“…The use of peritoneal dialysis may facilitate access to dialysis in some parts of the world. Several studies mainly from Brazil have shown that peritoneal dialysis can provide similar outcomes to other dialysis modalities in AKI [43,44,45]. …”

Section: Recognition and Management Of Aki In Western Countriesmentioning

confidence: 99%

Acute Kidney Injury in Western Countries

Bouchard

Mehta

2016

Kidney Dis

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Background: Acute kidney injury (AKI) is frequent and is associated with poor outcomes, including increased mortality, higher risk of chronic kidney disease, and prolonged hospital lengths of stay. The epidemiology of AKI mainly derives from studies performed in Western high-income countries. More limited data are available from Western low-income and middle-income countries (LMICs) located in Central and South America. Summary: In this review, we summarize the most recent data on the epidemiology of AKI in Western countries, aiming to contrast results from industrialized high-income countries with LMICs. The global picture of AKI in LMICs is not as well characterized as in the USA and Europe. In addition, in some LMICs, the epidemiology of AKI may vary depending on the region and socioeconomic status, which contributes to the difficulty of getting a better portrait of the clinical condition. In low-income regions and tropical countries, AKI is frequently attributed to diarrhea, infections, nephrotoxins, as well as obstetric complications. As opposed to the situation in high-income countries, access to basic care in LMICs is limited by economic constraints, and treatment is often delayed due to late presentation and recognition of the condition, which contribute to worse outcomes. In addition, dialysis is often not available or must be paid by patients, which further restricts its use. Key Messages: There are great disparities in the epidemiology of AKI between Western high-income countries and Western LMICs. In LMICs, education and training programs should increase the public awareness of AKI and improve preventive and basic treatments to improve AKI outcomes. Facts from East and West: (1) More than 90% of the patients recruited in AKI studies using KDIGO-equivalent criteria originate from North America, Europe, or Oceania, although these regions represent less than a fifth of the global population. However, the pooled incidence of AKI in hospitalized patients reaches 20% globally with moderate variance between regions. (2) The lower incidence rates observed in Asian countries (except Japan) may be due to a poorer recognition rate, for instance because of less systematically performed serum creatinine tests. (3) AKI patients in South and Southeastern Asia are younger than in East Asia and Western countries and present with fewer comorbidities. (4) Asian countries (and to a certain extent Latin America) face specific challenges that lead to AKI: nephrotoxicity of traditional herbal and less strictly regulated nonprescription medicines, environmental toxins (snake, bee, and wasp venoms), and tropical infectious diseases (malaria and leptospirosis). A higher incidence and less efficient management of natural disasters (particularly earthquakes) are also causes of AKI that Western countries are less likely to encounter. (5) The incidence of obstetric AKI decreased globally together with an improvement in socioeconomic levels particularly in China and India in the last decades. However, antenatal care and abortion ma...

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A randomized clinical trial of high volume peritoneal dialysis versus extended daily hemodialysis for acute kidney injury patients

Cited by 76 publications

References 30 publications

Acute kidney injury: risk factors and management challenges in developing countries

Acute kidney injury: risk factors and management challenges in developing countries

Peritoneal Dialysis Treatment Modality Option in Acute Kidney Injury

Acute Kidney Injury in Western Countries

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