A Randomized, Blinded, Prospective Trial to Compare the Safety and Efficacy of Three Bowel-Cleansing Solutions for Colonoscopy (HSG-01*)

Abstract

Preparatory PEG-EL1 (Klean-Prep) was significantly superior to PEG-EL2 (Endofalk) and NaP (Fleet Phospho-Soda) in achieving effective cleansing of the entire colon prior to colonoscopy. On the basis of these data, PEG-EL1 can be regarded as the "gold standard" for bowel cleansing prior to colonoscopy.

Improving quality of colonoscopy by adding simethicone to sodium phosphate bowel preparation

“…The success rate, total duration of colonoscopy, side effects of medication, endoscopist satisfaction, and patient satisfaction were compared between the two groups. Endoscopist satisfaction was evaluated for air bubbles and adequacy of colon preparation by a self-rated questionnaire with a 4-degree scale ranging from very poor to very good [10] . The side effects of the bowel preparation regimens were recorded.…”

“…The side effects of the bowel preparation regimens were recorded. Patient satisfaction was scored with a Visual Analog Scale, ranging from 0-10, where 0 represented "very poor" and 10 represented "excellent" [10] . The study was registered in the national clinical trials database (ClinicalTrials.gov identifier NCT00615303) and was approved by the Hospital Ethics Committee.…”

“…Unfortunately, none of the preparations meets all of the requirements [2][3][4] . Several studies have evaluated the efficacy and side effects of regimens for bowel preparation [3][4][5][6][7][8][9][10][11][12][13][14] . In 2006, three medical organizations (the American Society for Gastrointestinal Endoscopy, the American Society of Colon and Rectal Surgeons, and the Society of American Gastrointestinal and Endoscopic Surgeons) suggested that polyethyleneglycol (PEG) should be a gold standard for colonoscopic bowel preparation (Grade IA), and aqueous sodium phosphate (NaP) was an alternative regimen to PEG solution (Grade IA) [2] .…”

Preparo de cólon para colonoscopia com polietilenoglicol versus sulfato de magnésio em pacientes acima de 70 anos de idade

“…Entre os efeitos adversos, mencionam-se dor abdominal e náuseas. O regime de duas doses, com uma na noite anterior e outra na manhã que precede o exame melhora sua aceitação e a aderência por parte do paciente, além de mostrar-se superior quanto à lavagem do cólon, quando comparado com regimes de dose única 9,10 . Foi demonstrado também, que o regime de duas doses, sem restrição na dieta, melhora a qualidade da lavagem do cólon, sem interferir na tolerabilidade do preparo pelo paciente 11 .…”

High Quality Preparation to Colonospcopy Is a Key to Exact Diagnostics

“…Стандартом подготовки первой линии сегодня является применение раствора полиэтиленгликоля с электролитами в объеме 4 л, который высоко эффективен, и в большинстве случаев хорошо и удовлетворительно переносится даже пожилы-ми людьми. Широко применявшийся препарат на основе фосфата натрия, эффективность которого, в общем, сопо-ставима с ПЭГ, после накопления данных о случаях раз-вития фосфатной нефропатии и диэлектролитных рас-стройств, сегодня рассматривается лишь как альтернати-ва ПЭГ с электролитами при невозможности приема последнего [30][31][32][33][34][35]. Альтернативными препаратами для подготовки также являются магния цитрат, натрия сульфат.…”