A randomised oral fluoride retention study comparing intra-oral kinetics of fluoride-containing dentifrices before and after dietary acid exposure

Burnett, Gary R.; Nehme, Marc; Parkinson, Charles; Karwal, Ritu; Badrock, Thomas C; Thomas, Gavin Vaughan; Hall, Peter

doi:10.1016/j.archoralbio.2020.104891

Cited by 4 publications

(3 citation statements)

References 28 publications

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“…Several of these studies have used toothpastes as the source of fluoride. Although these are typically formulated with reasonable levels of fluoride, typically around 1000 ppm [ 85 ], levels of fluoride in saliva drop rapidly after brushing, so that after 30 min the concentration in saliva is around 1 ppm [ 86 ]. This level drops even further to around 0.02 ppm 12–18 h after brushing [ 80 ] but is still sufficient to shift the demineralization–remineralization balance back toward remineralization.…”

Section: Methodsmentioning

confidence: 99%

Fluoride exchange by glass-ionomer dental cements and its clinical effects: a review

Nicholson,

Sidhu,

Czarnecka

2023

Biomaterial Investigations in Dentistry

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The topic of fluoride release and uptake by glass-ionomer (glass polyalkenoate) dental cements is reviewed. The study was based on a literature search carried out using PubMed. The main key words used were glass-ionomer and fluoride , and further refinements were made by adding the keywords anti-microbial , anti-caries and remineralization . Papers were selected from the initial search, which concentrated on fundamental aspects of fluoride release, including kinetics and the influence of the cement composition, and resulting clinical performance against caries. Other relevant papers were cited where they added useful and relevant data. From these published papers, it was possible to explain the detailed mechanism of fluoride release by glass-ionomer cements and also its uptake. Fluoride release has been shown to be a two-step process. In neutral solutions, the steps can be divided into early wash-out and long-term diffusion. In acid conditions, the early wash-out remains, though with greater amounts of fluoride released, and the long-term release becomes one of slow dissolution. The effect of fluoride on the viability of oral micro-organisms has been described, and glass-ionomers have been shown to release sufficient fluoride to reduce the size and viability of adjacent populations of oral bacteria. The effect of low levels of fluoride on the remineralization of tooth tissue has been considered. Levels needed to increase remineralization are much lower than those needed to adversely affect oral bacteria, from which we conclude that glass-ionomers release sufficient fluoride to promote remineralization. Despite this, there remains uncertainty about their overall contribution to sound oral health, given the widespread use of other sources of fluoride, such as toothpastes.

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Section: Methodsmentioning

confidence: 99%

Fluoride exchange by glass-ionomer dental cements and its clinical effects: a review

Nicholson,

Sidhu,

Czarnecka

2023

Biomaterial Investigations in Dentistry

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“…For the preservation of the remaining teeth, dental materials with ion releasing properties and bioactive ingredients (fluoride, calcium, or phosphate ions) are essential for fluoride ion release and recharge, which initiates remineralization and improves tooth resistance to demineralization ( Burnett et al, 2020 , Raszewski et al, 2021 , Verma et al, 2015 ). Furthermore, the presence of these ions in oral fluids contributes to antibacterial and antifungal action ( Flisfisch et al, 2008 ).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the effectiveness of bioactive glass fillers against Candida albicans adhesion to PMMA denture base materials: An in vitro study

Gad

Abu-Rashid

Alkhaldi

et al. 2022

The Saudi Dental Journal

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“…One of the most popular caries prevention methods is fluoride delivery. Fluoride reacts with calcium and phosphate ions and forms fluorinated hydroxyapatite and fluoroapatite in the enamel structure, which are more resistant to demineralization [4]. Various preventive products act as fluoride ions donors.…”

Section: Introductionmentioning

confidence: 99%

Release and Recharge of Fluoride Ions from Acrylic Resin Modified with Bioactive Glass

Raszewski¹,

Nowakowska

Więckiewicz

et al. 2021

Polymers

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Background: Oral hygiene is essential for maintaining residual dentition of partial denture wearers. The dental material should positively affect the oral environment. Fluoride-releasing dental materials help to inhibit microbial colonization and formation of plaque as well as to initiate the remineralization process in the early cavity area. Aim: To evaluate fluoride ion release and recharge capacity, sorption, and solubility of polymethyl methacrylate (PMMA) dental resin modified with bioactive glass addition. Materials and methods: Two bioactive glass materials (5 wt% Kavitan, 10 wt% Kavitan, and 10 wt% Fritex) and pure 10 wt% NaF were added to dental acrylic resin. After polymerization of the modified resins, the release levels of fluoride anions were measured based on color complex formation by using a spectrophotometer after 7, 14, 28, and 35 days of storage in distilled water at 37 °C. Subsequently, specimens were brushed with a fluoride-containing tooth paste on each side for 30 s, and the fluoride recharge and release potential was investigated after 1, 7, and 14 days. Sorption and solubility after 7 days of storage in distilled water was also investigated. Results: The acrylic resins with addition of 10% bioactive glass materials released fluoride ions for over 4 weeks (from 0.14 to 2.27 µg/cm2). The amount of fluoride ions released from the PMMA resin with addition of 10 wt% Fritex glass was higher than that from the resin with addition of 10 wt% Kavitan. The acrylic resin containing 10 wt% NaF released a high amount of ions over a period of 1 week (1.58 µg/cm2), but the amount of released ions decreased rapidly after 14 days of storage. For specimens containing 5 wt% Kavitan glass, the ion-releasing capacity also lasted only for 14 days. Fluoride ion rechargeable properties were observed for the PMMA resin modified with addition of 10 wt% Fritex glass. The ion release levels after recharge ranged from 0.32 to 0.48 µg/cm2. Sorption values ranged from 10.23 μm/mm3 for unmodified PMMA resin to 12.11 μm/mm3 for specimens modified with 10 wt% Kavitan glass. No significant differences were found regarding solubility levels after 7 days. Conclusions: The addition of 10 wt% Fritex and 10 wt% Kavitan bioactive glass materials to heat-cured acrylic resin may improve its material properties, with bioactive fluoride ion release ability lasting for over 4 weeks. The resin modified with 10 wt% Fritex glass could absorb fluoride ions from the toothpaste solution and then effectively release them. Addition of fluoride releasing fillers have a small effect on sorption and solubility increase of the modified PMMA resin. Clinical significance: The addition of bioactive glass may be promising in the development of the novel bioactive heat-cured denture base resin.

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A randomised oral fluoride retention study comparing intra-oral kinetics of fluoride-containing dentifrices before and after dietary acid exposure

Cited by 4 publications

References 28 publications

Fluoride exchange by glass-ionomer dental cements and its clinical effects: a review

Fluoride exchange by glass-ionomer dental cements and its clinical effects: a review

Evaluation of the effectiveness of bioactive glass fillers against Candida albicans adhesion to PMMA denture base materials: An in vitro study

Release and Recharge of Fluoride Ions from Acrylic Resin Modified with Bioactive Glass

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