A Radiological Review of Ewing\'s Sarcoma of Mandible: A Case Report with One Year Follow-up

Krishna, KB Bimal; Thomas, Valsa; Jayasree, K; Kusumakumari, P.

doi:10.5005/jp-journals-10005-1200

Cited by 24 publications

(10 citation statements)

References 15 publications

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“…Even in a small area of Ewing's sarcoma, multiple therapy modalities are required due to the high risk of metastasis. 19 The treatment strategy for ES is characterized by multidisciplinary collaboration between pediatric oncologists, medical oncologists, radiation oncologists, and orthopedic surgeons. Approximately only 10% of the patients with Ewing's sarcoma survived before the introduction of chemotherapy as a management modality, which has now been drastically improved with 75% survival rates in patients with localized tumors.…”

Section: Discussionmentioning

confidence: 99%

Ewing's Sarcoma of Mandible: A Case Report with Review

Ahuja¹,

Puri²,

Gupta

et al. 2019

International Journal of Clinical Pediatric Dentistry

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Aim: To make dentists and pedodontists aware of a possible outcome of a rapidly growing swelling. Background: Ewing's sarcoma is a rare aggressive variant of small round cell tumors and is an uncommon malignancy that occurs usually in childhood. It constitutes 10-15% of all primary malignant tumors and represents the second most common malignant bone tumor occurring in children and young adults. Case description: We report a case of Ewing's sarcoma in an 11-year-old male child who reported with a rapidly progressing swelling in the left mandibular posterior region. Panoramic view and computed tomography showed characteristic moth eaten and sun-ray appearance. Fineneedle aspiration cytology revealed a small round cell tumor. Since the exact diagnosis is hard to achieve before biopsy, the condition poses a difficult diagnostic dilemma for the clinician. Histopathology was performed for the accurate diagnosis. Conclusion: Dentists and pedodontists should develop a high index of suspicion in diagnosing cases with rapidly enlarging intraoral or extraoral swellings as early and correct diagnosis may improve clinical management and survival for patients with this disease. Clinical significance: Our case report is an attempt to help the dental community in developing familiarity with the clinical presentation of Ewing's sarcoma.

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Section: Discussionmentioning

confidence: 99%

Ewing's Sarcoma of Mandible: A Case Report with Review

Ahuja¹,

Puri²,

Gupta

et al. 2019

International Journal of Clinical Pediatric Dentistry

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“…Overall survival is 60% at 5 years if there is no remote localization, and it decreases by half in the presence of initial metastases [10,11]. The most frequent localization is the diaphysis of the long bones, the pelvis, and the ribs.…”

Section: Discussionmentioning

confidence: 99%

The oral surgeon in the front-line of the diagnosis of Ewing sarcoma: a case report

Saleh¹,

Loison-Robert²,

Guillerminet³

et al. 2018

J Oral Med Oral Surg

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Introduction: Ewing's sarcoma is a primary malignant bone tumor that affects children and young adults. In rare cases, it affects the bones of the face. The diagnosis is difficult because signs are non-specific. Positive diagnosis is based on a cytogenetic examination showing a specific translocation of the EWS gene. Treatment involves a sequence including chemotherapy, oncological surgery and radiotherapy. Observation: The case presented is that of a 4-year old girl initially sent for suspicion of dental cellulitis. On clinical examination, she had recent mandibular dental mobility and a gingival mucosa swelling. Signs of bone lysis interesting the mandibular symphysis was observed on the orthopantomogram. She had no pain or symptoms indicating neoplasia. This atypical situation led to a bone biopsy who revealed the diagnostic of mandibular Ewing's sarcoma. A suitable medical care in a specialized unit was able to be started without delay. Discussion: The literature reports other cases also wrongly diagnosed as an infectious pathology of dental origin. Conclusion: This case shows that the diagnosis of mandibular Ewing's sarcoma must be evoked in front of any atypical mandibular lesion of the child, regardless of his age or sex. Physicians and dental surgeons specialized in oral surgery are then in the foreground to help establish early diagnosis and ensure rapid management by limiting the functional and aesthetic sequelae related to localization.

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“…919-21 Radiographically, ES could mimic a variety of pathological entities involving the jaws, and thus, it is aptly characterized as the “great imitator of bone pathology” by many authors. 22 An ill-defined, moth-eaten lytic lesion with or without cortical erosion and bone expansion is the most characteristic radiographic feature, 31323-25 while the commonly seen long bone periosteal “onion skin” reaction is rarely encountered in jaw lesions. 14-172627 Computed tomography scans and MRI have been well demonstrated as the most accurate approach for evaluating the extent of the bone destruction and the soft tissue involvement respectively.…”

Section: Discussionmentioning

confidence: 99%

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

Chatzistefanou

Kabesi

Paraskevopoulos

et al. 2016

International Journal of Clinical Pediatric Dentistry

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Ewing’s sarcoma (ES) is an uncommon aggressive bone malignancy that mainly affects children and adolescents. Mandible involvement is quite rare and usually represents metastasis from another skeletal site. Combined therapy including wide surgical resection and preoperative and postoperative chemotherapy has been demonstrated as the mainstay of therapeutic approach. As improved therapeutic modalities have significantly increased survival over the last decades, functional and esthetic reconstruction of the postmandibulectomy defect is usually necessary for patient’s total rehabilitation. We report a case of ES of the mandible with special consideration to the postresection spontaneous structural and functional regeneration of the mandible.How to cite this articleChatzistefanou I, Kabesi S, Paraskevopoulos K, Koliouskas D, Antoniades K. Ewing’s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration. Int J Clin Pediatr Dent 2016;9(3):273-277.

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A Radiological Review of Ewing\'s Sarcoma of Mandible: A Case Report with One Year Follow-up

Cited by 24 publications

References 15 publications

Ewing's Sarcoma of Mandible: A Case Report with Review

Ewing's Sarcoma of Mandible: A Case Report with Review

The oral surgeon in the front-line of the diagnosis of Ewing sarcoma: a case report

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

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A Radiological Review of Ewing\'s Sarcoma of Mandible: A Case Report with One Year Follow-up

Cited by 24 publications

References 15 publications

Ewing&#39;s Sarcoma of Mandible: A Case Report with Review

Ewing&#39;s Sarcoma of Mandible: A Case Report with Review

The oral surgeon in the front-line of the diagnosis of Ewing sarcoma: a case report

Ewing\'s Sarcoma of Mandible: An Impressive Case of Spontaneous Mandible Regeneration

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Ewing's Sarcoma of Mandible: A Case Report with Review

Ewing's Sarcoma of Mandible: A Case Report with Review