“…It is not worthwhile to spend the effort generating a biofortified crop for a given population if they are knowledgeable, prepared and not already willing to accept the technology or any changes in appearance of the biofortified crop [ 126 , 127 , 128 , 129 , 130 ]. New crop varieties with enhanced nutritional qualities must be evaluated by clinical trials, and select populations who can benefit most from them must be educated so that they understand how these advantages can make a difference in their community’s overall health [ 4 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 , 143 ]. Research and development of nutritionally enhanced “orphan crops” sorghum, millet, and pigeon pea, which are important to the world’s poor but overlooked by industrialized countries, must also be implemented.…”