A pseudolymphomatous reaction in soft tissue associated with phenytoin sodium.

Abstract

A pseudolymphomatous reaction involving subcutaneous tissue and underlying skeletal muscle is described in a woman who was receiving phenytoin sodium and phenobarbitone. The histological appearance was of nodular, densely cellular tissue composed of histiocytes, plasma cells, lymphocytes, fibroblasts, and occasional polymorphonuclear cells. The significance of this finding is briefly considered in relation to the existing literature.

Benign lymphoid hyperplasia (pseudolymphoma) of soft tissue

“…We describe a case of pseudolymphoma of the soft tissues, a site that has been reported only once previously. A single case report describing a pseudolymphomatous reaction of the soft tissues was published by J. N. Wilden and C. A. Scott in 1978 [1]. The patient was a 31-year-old woman who presented with intermittent painless swellings of the back, head, and neck.…”

Gastric pseudolymphoma: Its three subtypes and relation to lymphoma

“…SEUDOLYMPHOMA is a curious entity occumng in P a wide variety of sites including the orbit,' skin,2 salivary gland^,^.^ mediastinal' and abdominal lymph l~n g ,~.~ rectum," small inte~tine,'~-l~ and even the breastI4 and soft tissue. 15 Florid lesions of the thyroid" might even be included. The stomach" in particular has been one of the most common locations, and the diagnostic criteria of gastric pseudolymphoma have been previously outlined.…”