Benign lymphoid hyperplasia (pseudolymphoma) of soft tissue

McElroy, Michele; Kulidjian, Anna; Sumit, Rana; Weidner, Noel

doi:10.1016/j.humpath.2011.02.006

Cited by 5 publications

(5 citation statements)

References 16 publications

(18 reference statements)

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“…However, the final diagnosis was BLH in the buccal mucosa, based on the histological features. Many cases of the lymphoproliferative disease have been reported in the gastrointestinal tract, lung, skin, and nose [3,6]. In the oral mucosa, the occurrence of lymphoproliferative disease is rare.…”

Section: Discussionmentioning

confidence: 99%

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A Case of Benign Lymphoid Hyperplasia of Buccal Mucosa

Watanabe¹,

Fukumoto²,

Hiroshima³

et al. 2017

ojdom

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Benign lymphoid hyperplasia (BLH) is a rare type of lymphoproliferative disease of the oral mucosa. The present study reports a 61-year-old man who presented to the hospital with a soft polyp formation in the left buccal mucosa. He was suspected with a granuloma from cracked tooth, and an excisional biopsy was performed under local anesthesia. The histopathological examination of the specimen confirmed BLH. The patient's condition was well and free of disease at 2 years after the surgery. In this present case study, we concluded that BLH may be considered as a differential diagnosis of lymphoid disease in the oral soft tissue.

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Section: Discussionmentioning

confidence: 99%

“…Benign lymphoid hyperplasia (BLH), which is also known as reactive lymphoid hyperplasia, pseudolymphoma and follicular lymphoid hyperplasia, is a rare type of lymphoproliferative disease of the oral mucosa. The histological features of the lymphatic-tissue reveal its response to a variety of stimulations [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

A Case of Benign Lymphoid Hyperplasia of Buccal Mucosa

Watanabe¹,

Fukumoto²,

Hiroshima³

et al. 2017

ojdom

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“…8 Benign lymphoid hyperplasia (pseudolymphoma) has been reported to be found in the skin, lungs, orbit, conjunctiva, eyelids, gastrointestinal tract, liver, scrotum, vagina, and breast. 7 Cutaneous pseudolymphoma can be idiopathic or a reaction to various antigens.…”

Section: Discussionmentioning

confidence: 99%

A Rare Kind of Lymphoma in a Patient on Treatment With Two Different Biological Agents

et al. 2015

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“…Do manifestacji zmian o charakterze NLH może dochodzić również w innych umiejscowieniach, głównie w jelitach [2,3]. Dotychczas opisano także pojedyncze przypadki łagodnych rozrostów limfoidalnych w tkankach miękkich kończyny dolnej [4] oraz w zatoce klinowej [5].…”

Section: Wstępunclassified

Guzkowy Rozrost Limfoidalny—Rzadki Przypadek Choroby Limfoproliferacyjnej w Płucach

Rogoziński¹,

Bruliński²,

Malinowski³

et al. 2012

Advances in Respiratory Medicine

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Nodular lymphoid hyperplasia (NLH) belongs to a very rare, mild, lymphoproliferative disease of unestablished aetiology historically included in the group of pseudolymphomas. Its existence was controversial for many years, until modern techniques of pathomorphological diagnosis approved it as a separate entity of lung disease. It manifests in the form of well limited nodules localized in the lungs, which are mostly identified accidentally. Clinical symptoms are rare and nonspecific; the disease usually occupies only one lung. Pathomorphological diagnosis requires immunohistochemical designation of expressions of numerous antigens in order to exclude malignant lymphoma of the lungs. Surgical resection is used in cases of larger nodules; the smaller ones require periodic observation, and the prognosis is good. The authors describe the case of 65-year-old woman with pulmonary nodules which were detected accidentally in the right lung. The patient was qualified for right-sided videothoracoscopy and removal of the lung nodule. In classic HE staining of the histological material, the presence of lymphoid infiltration of the lungs was revealed, which formed lymph follicles with reactive germinal centres. In order to differentiate from the malignant lymphatic expansion, immunohistochemical designations were made, which showed positive expression of CD20 antigen in the B cell zone, positive expression of the CD3 antigen in the T cells zone, positive expression of CD23 antigen in the lymph follicles, negative expression of bcl-2 in the lymph follicles, and positive expression of MIB-1 in the germinal centres of lymph follicles. Such a histopathological and immunohistochemical picture provided the basis for diagnosis of nodular lymphoid hyperplasia of the lung.

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Benign lymphoid hyperplasia (pseudolymphoma) of soft tissue

Cited by 5 publications

References 16 publications

A Case of Benign Lymphoid Hyperplasia of Buccal Mucosa

A Case of Benign Lymphoid Hyperplasia of Buccal Mucosa

A Rare Kind of Lymphoma in a Patient on Treatment With Two Different Biological Agents

Guzkowy Rozrost Limfoidalny—Rzadki Przypadek Choroby Limfoproliferacyjnej w Płucach

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