A Prospective Study to Evaluate Cardiac Functions in Postmastectomy Left-Sided Breast Cancer Patients Receiving Doxorubicin Based Chemotherapy and Chest Wall Irradiation
Abstract:This prospective single institution study was carried out with 55 patients to evaluate the cardiac functions in left sided post mastectomy breast cancer patients who received Doxorubicin based chemotherapy with chest wall irradiation. Our study reported only 18% cardiotoxicity in contrast to about 30% in similar studies. There was a decline in the left ventricular ejection fraction after chemotherapy. Radiation did not affect left ventricular function much. The right ventricular systolic dysfunction observed i… Show more
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