A prospective study of stability and change over 2 years of affective temperaments in 14–18 year-old Italian high school students

Placidi, G.F.; Maremmani, Icro; Signoretta, S; Liguori, A; Akiskal, Hagop S.

doi:10.1016/s0165-0327(98)00182-7

Cited by 42 publications

(21 citation statements)

References 38 publications

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“…Along this line of thought, Akiskal designed the TEMPS-A as a 110 item true/false self-rated questionnaire with scales that measure dysthymic, cyclothymic, hyperthymic, irritable, and anxious temperaments (Akiskal et al, in press). An earlier version of this scale, the TEMPS-I, has been shown to have very good reliability and internal consistency, and the dysthymic, hyperthymic, and cyclothymic scales of the TEMPS-I have shown moderate stability over time (Placidi et al, 1998b;Akiskal et al, 1998;Placidi et al, 1998a). According to Cloninger's model, temperament and character dimensions interact to form an individual's personality with certain interactions leading to the various mood disorders as well as other psychiatric disorders.…”

Section: Introductionmentioning

confidence: 99%

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Familiality of temperament in bipolar disorder: support for a genetic spectrum

Evans

Akiskal

Keck

et al. 2005

Journal of Affective Disorders

160

127

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Section: Introductionmentioning

confidence: 99%

“…As described above, these scales have been shown to have moderate stability over time (Placidi et al, 1998a;Cloninger et al, 1994), however, the longitudinal effect of state changes on temperament and character traits remains to be resolved.…”

mentioning

confidence: 99%

Familiality of temperament in bipolar disorder: support for a genetic spectrum

Evans

Akiskal

Keck

et al. 2005

Journal of Affective Disorders

160

127

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“…We examined the stability of affective temperaments over 6 years, which is much longer than in previous studies [39,40,[47][48][49] . Taken in conjunction with a report that TEMPS-measured cyclothymic temperament in healthy adults represents a behavioral endophenotype as aggregated in families with bipolar disorder [62] , the present study strongly suggests that affective temperaments as measured by TEMPS-A may be considered stable traits, and that it may be useful for future studies to explore endophenotypes in mood disorders as manifested in TEMPS-A affective temperaments.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, we assessed stability by using differential stability, defined as Pearson correlation coefficients of affective temperament scores across 2 points in time. Differential stability is the most frequently used concept in previous studies, including all studies [39,40] on the longitudinal stability of TEMPS-measured affective temperaments.…”

Section: Introductionmentioning

confidence: 99%

Six-Year Stability of Affective Temperaments as Measured by TEMPS-A

Kawamura¹,

Akiyama

Shimada³

et al. 2010

Psychopathology

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Background: A number of psychopathological and neurobiological studies on affective temperament have been conducted based on the assumption that temperament is a stable trait. However, few studies have actually assessed the long-term stability of affective temperament. The objective of this study is to evaluate the 6-year stability of affective temperaments as measured by the Temperament Evaluation of Memphis, Pisa, Paris and San Diego – Autoquestionnaire version (TEMPS-A) in a non-clinical adult population. Sampling and Methods: Study participants consisted of 178 Japanese white-collar workers (103 males and 75 females; mean age = 38.5 years, SD = 7.8) who completed the Japanese version of TEMPS-A twice over a 6-year interval, and who did not have either past or current DSM-IV affective, anxiety or psychotic disorders, as diagnosed with the Mini-International Neuropsychiatric Interview. The long-term stability of affective temperaments as measured by TEMPS-A was assessed by analyzing Pearson correlation coefficients for temperament scores over a 6-year period. Results: Temperament scores were moderately to highly correlated over the 6-year period (depressive temperament, r = 0.59; cyclothymic temperament, r = 0.68; hyperthymic temperament, r = 0.82; irritable temperament, r = 0.66; anxious temperament, r = 0.74; p < 0.01 for all values). Pearson coefficients were in the range of 0.61–0.83 for males and 0.51–0.79 for females, while they were 0.56–0.85 for younger and 0.63–0.77 for older participants. All correlations were significant at p < 0.01, irrespective of temperament type, gender and age. Conclusions: Affective temperaments as measured by TEMPS-A exhibited good long-term stability and were robust, irrespective of temperament type, gender and age. Affective temperaments as measured by TEMPS-A may be considered to be stable traits, providing a sound basis for psychopathological and neurobiological studies. Limitations of this study include the fact that our sample was not drawn from the general community, it was entirely composed of Japanese participants and the size was not large.

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“…Its use in previous family studies of BPD, along with demonstrated validity and reliability, makes it a particularly useful tool for studies of candidate endophenotypes. The TEMPS-A is based on interview versions of the dysthymic, cyclothymic, hyperthymic, and irritable temperaments (Akiskal and Weise 1992) and was originally validated in a large cohort of Italian students (n ¼ 1,010) Placidi et al 1998). A four-factor structure, similar to that of the original interview version, was described in the validation sample.…”

Section: Evidence For Temperamental Endophenotypes For Bipolar Disordermentioning

confidence: 99%

Clinical Endophenotypes for Bipolar Disorder

Glahn

Burdick

2010

Behavioral Neurobiology of Bipolar Disorder and Its Treatment

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Although twin, family, and adoption studies demonstrate that bipolar disorder (BPD) is substantially heritable, the molecular genetic basis for this illness remains elusive. Given evidence that genes predisposing to BPD may be transmitted without expression of the clinical phenotype, interest has arisen in developing endophenotypes - indicators of processes mediating between genotype and phenotype. Patients with BPD have subtle neuropsychological abnormalities, even during periods of symptom remission. Some of these neurocognitive deficits are present in unaffected family members of probands with BPD, suggesting that these measures may be quantitative endophenotypes for the disorder. Similarly, BPD is associated with specific personality traits (e.g., reduced inhibition, increased risk-taking) that have been observed in both affected individuals and their family members. In this chapter, we review the evidence for candidate neurocognitive and personality endophenotypes for BPD. We conclude that neurocognitive and personality traits appear to be appropriate endophenotypes for BPD, suggesting that these measures share some genetic factors with the illness.

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A prospective study of stability and change over 2 years of affective temperaments in 14–18 year-old Italian high school students

Cited by 42 publications

References 38 publications

Familiality of temperament in bipolar disorder: support for a genetic spectrum

Familiality of temperament in bipolar disorder: support for a genetic spectrum

Six-Year Stability of Affective Temperaments as Measured by TEMPS-A

Clinical Endophenotypes for Bipolar Disorder

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