A Prospective Study of Quality of Life in Head and Neck Cancer Patients. Part II: Longitudinal Data

Bjordal, Kristin; Ahlner-Elmqvist, Marianne; Hammerlid, Eva; Boysen, Morten; Evensen, Jan F.; Biörklund, Anders; Jannert, Magnus; Westin, Thomas; Kaasa, Stein

doi:10.1097/00005537-200108000-00022

Cited by 287 publications

(264 citation statements)

References 15 publications

(32 reference statements)

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“…Regarding radiation therapy side effects, according to our data as well as others', 29 the H&N35 seems to be very sensitive, indicating excellent discriminant validity in this respect. Stoeckli et al 30 do have results that differ from these; however, it is presumable that their data could not reach statistical significance levels because of the sample size-only 16 of their study participants had been irradiated.…”

Section: Discussionsupporting

confidence: 83%

Validation of the EORTC QLQ‐C30 and EORTC QLQ‐H&N35 in patients with laryngeal cancer after surgery

et al. 2008

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Background. The aim of this study was to test the validity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core Module (QLQ-C30) and Head and Neck Module (QLQ-H&N35) for patients who have undergone surgery due to laryngeal cancer.Methods. A total of 323 patients from 6 different centers in Germany who had been operated on completed the QLQ-C30 and the QLQ-H&N35 in addition to being surveyed in a personal interview.Results. Multitrait scaling analysis confirmed the proposed scale structure of both questionnaires. Cronbach's alpha of the QLQ-C30 scales ranged from 0.64 (Cognitive Functioning) to 0.94 (Global Health Status); the alpha of the QLQ-H&N35 ranged from 0.55 (Speech) to 0.90 (Sexuality). Known-groups comparisons showed multiple differences in sociodemographic and clinical variables.Conclusion. It can be concluded that the QLQ-H&N35, in conjunction with the QLQ-C30, is a reliable instrument that is able to differentiate between diverse groups of patients with laryngeal cancer after surgery. V

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Section: Discussionsupporting

confidence: 83%

Validation of the EORTC QLQ‐C30 and EORTC QLQ‐H&N35 in patients with laryngeal cancer after surgery

et al. 2008

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“…In some studies no gender difference was noticed (23) whereas in others a worse QOL was reported for women (24 -26). Similarly, in some studies no influence of age on QOL was found (27) while in others better QOL was found among younger patients (28). Although not apparent in our study, tumour site has been reported as having a definite influence on the QOL among head and neck cancer patients (29).…”

Section: Discussionsupporting

confidence: 46%

Morbidity And Quality Of Life Among Head And Neck Cancer Patients Treated With Radical Radiotherapy

Mm¹,

Jf²,

Nyabola³

et al. 2009

E Af Med Jrnl

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Objectives:To determine the relative frequency of acute radiation morbidity and their perceived effect on quality of life among head and neck cancer patients treated with radical radiotherapy. Design: A cross-sectional study. Setting: Kenyatta National Hospital, Nairobi. Subjects: Thirty eight patients comprising 28 males and 10 females with ages ranging between 21 and 69 years were evaluated. Results: Most of the tumours occurred in the nasopharynx (38.6%). The rest of the tumours were equally divided between the oral cavity and larynx (31.6%). All tumours except two were carcinomas. The two exceptions were a glomus tumour and a malignant melanoma. The patients had received doses of radiotherapy ranging between 58.5 Grey and 75.5 Grey. Of the 38 patients, 22 (53%) completed their treatment in the prescribed time while 16 (47%) had treatment interruption on account of radiation morbidity. The cumulative radiation done at the time of interruption ranged between 20 and 46 Grey. The most frequent symptom was dryness of the mouth while the most troublesome symptom was difficulty in tasting foods. The quality of life (QOL) did not vary by age, gender or tumour site. Patients who had treatment interruption had a better QOL than those who did not. Conclusion:This study provides information that should aid in communicating with the head and neck cancer patients scheduled for radiotherapy and in the design of preventive and interventional strategies aimed at enhancing patient support and rehabilitation.

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“…observed a general trend of significant deterioration on quality of life during treatment but a slow recovery during the 12 following months (Bjordal et al, 2001).…”

Section: Cancer Treatment and Side-effectsmentioning

confidence: 93%

Comparison of Psychosocial Outcomes in Head and Neck Cancer Patients Receiving a Coping Strategies Intervention and Control Subjects Receiving No Intervention

Vilela

Nicolau²,

Mahmud³

et al. 2006

J Otolaryngol

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A Prospective Study of Quality of Life in Head and Neck Cancer Patients. Part II: Longitudinal Data

Abstract: Detailed knowledge about the differences between groups and changes over time may aid us in the communication with patients and in the design of intervention studies focusing on improvement of the support and rehabilitation of patients with head and neck cancer.

Cited by 287 publications

References 15 publications

Validation of the EORTC QLQ‐C30 and EORTC QLQ‐H&N35 in patients with laryngeal cancer after surgery

Validation of the EORTC QLQ‐C30 and EORTC QLQ‐H&N35 in patients with laryngeal cancer after surgery

Morbidity And Quality Of Life Among Head And Neck Cancer Patients Treated With Radical Radiotherapy

Comparison of Psychosocial Outcomes in Head and Neck Cancer Patients Receiving a Coping Strategies Intervention and Control Subjects Receiving No Intervention

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