A Prospective, Randomized, Double-blind Comparison of the Anesthetic Efficacy of Two Percent Lidocaine with 1:100,000 and 1:50,000 Epinephrine and Three Percent Mepivacaine in the Intraoral, Infraorbital Nerve Block

Berberich, Gerhard; Reader, Al; Drum, Melissa; Nusstein, John; Beck, Mike

doi:10.1016/j.joen.2009.08.007

Cited by 25 publications

(25 citation statements)

References 13 publications

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“…The local anesthetic solution might not be able to diffuse until the apical area of the palatal root (17). This is evident in studies comparing the anesthesia success in maxillary first molars with incisors (17,27). In the present study, it was noticed that the majority of the failure cases in the buccal infiltration group either presented with pain during access preparation or the instrumentation of canals, especially the palatal canal.…”

Section: Discussionmentioning

confidence: 62%

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A Prospective, Randomized, Single-blind Comparative Evaluation of Anesthetic Efficacy of Posterior Superior Alveolar Nerve Blocks, Buccal Infiltrations, and Buccal Plus Palatal Infiltrations in Patients with Irreversible Pulpitis

Aggarwal

Singla

Miglani

et al. 2011

Journal of Endodontics

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Section: Discussionmentioning

confidence: 62%

“…There is very limited literature comparing the anesthetic efficacy of 2% lidocaine with different concentrations of epinephrine in PSA blocks. However, the available literature suggests that 2% lidocaine with 1:100,000 epinephrine will have the same anesthetic efficacy as that of 2% lidocaine with 1:200,000 epinephrine (27,28).…”

Section: Discussionmentioning

confidence: 99%

A Prospective, Randomized, Single-blind Comparative Evaluation of Anesthetic Efficacy of Posterior Superior Alveolar Nerve Blocks, Buccal Infiltrations, and Buccal Plus Palatal Infiltrations in Patients with Irreversible Pulpitis

Aggarwal

Singla

Miglani

et al. 2011

Journal of Endodontics

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“…Further, pain may influence or be influenced by anxiety levels related to dental treatment. The use of a LAVA (injection) can also produce extreme pain and fear, at least momentarily, in some patients 11,12. On the other hand, when a dentist judges that it is possible to go on with a procedure without the use of a LAVA, patients may also exhibit discomfort, anxiety, and pain.…”

Section: Discussionmentioning

confidence: 99%

Glucose levels and hemodynamic changes in patients submitted to routine dental treatment with and without local anesthesia

Bortoluzzi

Manfro

Nardi

2010

Clinics

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OBJECTIVE:The aim of this study was to (1) observe the extent to which hemodynamic and glucose measurements change in patients submitted to a dental procedure with and without a local anesthetic and a vasoconstrictor (LAVA; 2% mepivacaine with adrenaline 1∶100,000) and (2) correlate those parameters with the patients' anxiety levels.METHOD:This was an unblinded, random, prospective, and observational study with paired groups. Patients were evaluated during two different consultations during which they either did or did not receive a local anesthetic/vasoconstrictor.RESULTS:Thirty‐seven patients ranging in age from 18 to 45 years (mean 30.4 ± 5.5 years) were evaluated. Hemodynamic parameters, including systolic blood pressure, diastolic blood pressure, heart rate, and glucose levels, did not change significantly in healthy patients, regardless of whether a LAVA was administered during the dental treatment.CONCLUSION:The patients' anxiety statuses neither varied significantly nor showed any correlation with the studied hemodynamic parameters and glucose levels, regardless of whether local anesthetics were used.

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“…Mepivacaine, on the other hand is a short acting anesthetic, although there are controversy. (Berberich, Reader, Drum Nusstein, & Beck, 2009;Ding, Zhu, Wu, & Cao, 2008) Uzeda examined systolic and diastolic blood pressure changes in healthy patients and those with controlled blood pressure presenting for dental extraction and receiving local anesthetics with vasoconstrictors. The patients were examined in the waiting room, when entering the surgery room and ten minutes after the injection.…”

Section: Introductionmentioning

confidence: 99%

Comparative Assessment of the Effects of Three Local Anesthetics: Lidocaine, Prilocaine, and Mepivacaine on Blood Pressure Changes in Patients with Controlled Hypertension

Hashemi¹,

Ladez²,

Moghadam³

2016

GJHS

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Background: Given large number of patients with hypertension attending dental clinics and the profound effects of local anesthetics containing vasoconstrictors, this study aimed to compare the effects of lidocaine 2% + epinephrine, prilocaine 3% + felypressin0.03, and mepivacaine 3% on blood pressure changes. Methods:The current study was carried out from May 2014 to February 2015.Patients with controlled hypertension (systolic blood pressure<159.94 mmHg before the injection) who attended Zahedan dental school (Zahedan , Iran) for the extraction of a mandibular tooth were selected and randomly allocated to three groups of 20. Groups 1-3 received lidocaine 2% + epinephrine, prilocaine 3% + felypressin 0.03 units, and mepivacaine3%, respectively. Patients were only included if they were injected with a maximum of two 1.8 ml cartridges (3.6 ml) for tooth extraction (maximum epinephrine dose of 0.04 mg was maintained in systemic patients).The collected data were analyzed using the analysis of variance (ANOVA) in SPSS 19.0. (SPSS Inc., Chicago, IL, USA)Results: No significant differences were observed between the systolic and diastolic blood pressure of the three groups. The three evaluated local anesthetic solutions had similar effects in patients with controlled hypertension. Conclusion:While no significant changes in blood pressure were observed in three groups, all dental procedures on the mentioned group of patients have to be performed under careful monitoring and aspiration. Moreover, the maximum epinephrine dose (0.04mg) should never be exceeded in these patients.

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A Prospective, Randomized, Double-blind Comparison of the Anesthetic Efficacy of Two Percent Lidocaine with 1:100,000 and 1:50,000 Epinephrine and Three Percent Mepivacaine in the Intraoral, Infraorbital Nerve Block

Cited by 25 publications

References 13 publications

A Prospective, Randomized, Single-blind Comparative Evaluation of Anesthetic Efficacy of Posterior Superior Alveolar Nerve Blocks, Buccal Infiltrations, and Buccal Plus Palatal Infiltrations in Patients with Irreversible Pulpitis

A Prospective, Randomized, Single-blind Comparative Evaluation of Anesthetic Efficacy of Posterior Superior Alveolar Nerve Blocks, Buccal Infiltrations, and Buccal Plus Palatal Infiltrations in Patients with Irreversible Pulpitis

Glucose levels and hemodynamic changes in patients submitted to routine dental treatment with and without local anesthesia

Comparative Assessment of the Effects of Three Local Anesthetics: Lidocaine, Prilocaine, and Mepivacaine on Blood Pressure Changes in Patients with Controlled Hypertension

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