A prospective observational study on assessment of adverse drug reactions in the in-patients of general medicine department at a tertiary care hospital

Abstract

According to the World Health Organization (WHO), Adverse Drug Reaction (ADR) is defined as "a response to a dangerous and unintended drug, which occurs in doses commonly used for prophylaxis, diagnosis, treatment or physical therapy" (Shukla et al., 2017). Although India accounts for 10% of global drug use, the reported ADR of drugs is 2%. This is mainly due to the poor report of drug abuse in India (Bahri, 2016). The incidence of ADRs as a whole leads to emergency admissions ranging from 0.2% to 41.3% worldwide, while 28.9% are safe (Palanisamy, 2013). Hospital admissions for ADR ranged from 2.9% to 5.6%. About 35% of patients in hospitals receive ADR. In India, the incidence of ADR is between 5.9 to 22.3% while deaths due to ADR accounts as 1.8% (Sivasankaaran et al., 2016). Many factors can put a patient at the forefront of the diagnosis of ADR patients with one or more risk factors for ADR including the pharmacy of Poly, many diseases and current, age, drug characteristics, gender, race and genetic factors (G. Parthasarathi, Sten Olsson). The purpose of this study was to evaluate and evaluate Adverse Drug Reaction with reasonable determination in patients admitted to the General Department of Health of a tertiary education hospital.