A Prospective Observational Study on Aetiology, Complications and Drug Related Problems of Liver Disorders in a Tertiary Care Teaching Hospital

Abstract

Liver Disease is mainly caused due to the Alcohol intake. Globally alcohol, drug induced liver disorders, hepatitis are the most common liver disorders finally leading to cirrhosis.The main aim of the study to Identify the Aetiology, Complications, Drug related problems and Therapeutics outcomes of the liver disorders among the patients of the general medicine department.To evaluate etiological factors involved in various liver disorders and liver diseases leading to cirrhosis. A hospital based, Prospective Observational study was carried out in general medicine in patient ward. According to the inclusion and exclusion criteria the patient were enrolled after obtaining their consent.During this period we found the 150 patients admitted in the general medicine ward were males 125(83.33%), females 25(16.66%). In our study majority of the patients belongs to the age groups 41-50(47%, 31.34%) Followed by 31-40(39%, 26%). Various Liver Disorders are found in our study were DCLD (58%), Viral Hepatitis (14%), Cirrhosis (13.33%), ALD (1.33%). Various aetiological factors were Alcohol, Smoking, Drug abuse, Idiopathic, Abdominal pain. The most common drugs were given to the patient was antibiotic. The study emphasizes the need to improve awareness of the patients on liver diseases to promote early diagnosis, alcohol abstinence and reduce mortality. Hence there is a need to increase the involvement of clinical pharmacist in designing appropriate therapeutic regimen along with other health care professionals, with the ultimate goal of preventing mortality due to liver disorders.