A prospective observational study for the evaluation of maternal and fetal outcome in patient with eclampsia

Abstract

Background: Eclampsia continues to be a measure health issue in developing country. In order to get a comprehensive data on eclamptic patients we conduct a prospective observational study to address the maternal and fetal complication during pregnancy.Methods: It is a prospective observational study conducted in a tertiary care medical college between the periods September 2016 to February 2017. During the period all patients with eclampsia admitted to the labour room were taken. Any patients with known epilepsy were excluded from the study.Results: During the period 3780 women were admitted to the labour room, out of which 56 women had eclampsia with an incidence of 1.48%. Out this antenatal eclampsia was most common with an incidence of 91.08% followed by intra partum 4 (7.14%) and postpartum eclampsia 1 (1.78%). Majority of patients 54 (96.43%) were unbooked or inadequately supervised. Most of the patient had normalization of blood pressure after oral nifedipine 46 (82.14%), only 10 (17.86%) patient required additional injection labetalol for control of blood pressure. The maternal complications were placental abruption 8 (14.28%), HELLP 6 (10.71%), pulmonary edema 1 (1.78%), acute renal failure 1 (1.78%), DIC 1 (1.78%) and maternal death 2 (3.57%). Out of fifty six babies delivered 42 (75%) had live birth and 14 (25%) had still birth. A total of 17 (40.42%) had IUGR, 17 (40.47%) require SNCU admission post-delivery.Conclusions:Eclampsia still remains the major cause of maternal and fetal morbidity. In low resource countries improvement in health care facility, adequate antenatal supervision, and timely referral will reduce the maternal and fetal complication.

Retrospective cohort study: Clinical presentation and outcomes of pre-eclampsia and eclampsia at Kenyatta National Hospital, Nairobi, Kenya

“…Babies born to EO-PE women were more likely to experience respiratory distress syndrome, necrotizing enterocolitis, and neonatal jaundice than those whose mothers had LO-PE. This resonates with other research finding impaired neonatal growth along with higher perinatal mortality and morbidity among EO-PE mothers than among non-PE as well as LO-PE women 35,41,42 .…”

Clinical presentation and outcomes of pre-eclampsia and eclampsia at a national hospital, Kenya: A retrospective cohort study

“…In addition to self-referrals by well-informed women, better diagnostic and surveillance capacities are necessary. ANC also involves specialized follow-up and control of chronic and gestational hypertension, availability and correct administration of drugs, timely delivery with optimum neonatal care, and critical and intensive maternal care [35][36][37]. Adherence to stricter treatment protocols for controlling hypertension in pregnancy and appropriate use of recommended drugs regimens for women exhibiting blood pressure of 150/100, has been shown to reduce pregnancy risks especially in EO-PE [38][39][40].…”