2012
DOI: 10.3109/01676830.2012.689080
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A Prospective, Multicentre Study of Malignant and Premalignant Lesions at the Base of Periocular Cutaneous Horns

Abstract: The incidence of malignant and pre-malignant lesions present at the base of periocular cutaneous horns was 36% with 8% of them being malignant. It is important to perform an excision biopsy with histological diagnosis of the base of the cutaneous horn as there are no definite clinical features that point towards a potential for malignancy.

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Cited by 9 publications
(3 citation statements)
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“…In our patient, the cutaneous horn was masking keratotic basal cell carcinomas (BCC), which is a well-described but uncommon variant of BCC. The shortest presenting duration of basal cell carcinoma with overlying cutaneous horn reported in the literature is nine months [4], as compared to the two-month duration in our case, which is the shortest duration reported till now. Histologically, a keratotic BCC shows islands of basaloid cells with nuclei demonstrating peripheral palisading, similar to the solid or nodular form of BCC.…”
Section: Discussioncontrasting
confidence: 58%
“…In our patient, the cutaneous horn was masking keratotic basal cell carcinomas (BCC), which is a well-described but uncommon variant of BCC. The shortest presenting duration of basal cell carcinoma with overlying cutaneous horn reported in the literature is nine months [4], as compared to the two-month duration in our case, which is the shortest duration reported till now. Histologically, a keratotic BCC shows islands of basaloid cells with nuclei demonstrating peripheral palisading, similar to the solid or nodular form of BCC.…”
Section: Discussioncontrasting
confidence: 58%
“…93 Various types of associated lesions can be found at the base of the keratin mound, which may be benign, premalignant, or malignant. The hyperkeratotic activity in the base lesion results in an unusually cohesive keratinized material and the formation of a protruding keratin horn.…”
Section: Sweat Gland Tumorsmentioning
confidence: 99%
“…The hyperkeratotic activity in the base lesion results in an unusually cohesive keratinized material and the formation of a protruding keratin horn. 93 Actinic keratoses are epidermal dysplasias or carcinomas in situ derived from neoplastic keratinocytes and occur after prolonged sun exposure. 93 Tambe and associates 93 studied 25 specimens of cutaneous horns.…”
Section: Sweat Gland Tumorsmentioning
confidence: 99%