A prospective clinical trial comparing Biobrane ® Dressilk ® and PolyMem ® dressings on partial-thickness skin graft donor sites

Schulz, Alexandra; Depner, Christian; Lefering, Rolf; Kricheldorff, Julian; Kästner, Sonja; Fuchs, Paul Christian; Demir, Erhan

doi:10.1016/j.burns.2014.12.016

Cited by 24 publications

(20 citation statements)

References 37 publications

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“…Reduction of wound‐related pain is an important part of donor site wound management . The survey by Geary and Tiernan highlighted that pain reduction was of prime importance among consultant plastic surgeons when examining the properties of donor site wound dressings.…”

Section: Discussionmentioning

confidence: 99%

“…54 Reduction of wound-related pain is an important part of donor site wound management. 13,54 The survey by Geary and Tiernan 15 highlighted that pain reduction was of prime importance among consultant plastic surgeons when examining the properties of donor site wound dressings. Whilst comfort related to the wearing of a donor site wound dressing is clearly important, dressing removal can also exacerbate the patient's experience of pain.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, some studies did not provide operational definitions of healing, which increased the risk of systematic error. Other studies were at risk of researcher bias by not identifying the level of training or experience of the assessors . Eight studies did not have identified days for assessing healing, and this makes it difficult to determine the precise day of healing and reduces the reliability of the findings.…”

Section: Methodological and Academic Rigour Of Studiesmentioning

confidence: 99%

“…Whilst there is consensus that the donor site wound should be managed in a way that maximises patient comfort, reduces pain, and promotes rapid healing, it has been demonstrated by several authors that there is considerable variation in the management of donor site wounds between institutions, with clear incongruities between practice and published evidence …”

Section: Introductionmentioning

confidence: 99%

“…8,9 In recognition of this, a pain-free dressing is a consistently desirable quality of a wound dressing in both adult and paediatric populations. 10,11 Whilst there is consensus that the donor site wound should be managed in a way that maximises patient comfort, reduces pain, and promotes rapid healing, 5,12,13 it has been demonstrated by several authors that there is considerable variation in the management of donor site wounds between institutions, with clear incongruities between practice and published evidence. 11,14,15 The aim of this review was to critically review the evidence relating to the efficacy of dressing materials on a split-thickness skin graft donor site wound in relation to promoting rapid healing and reducing patient pain.…”

mentioning

confidence: 99%

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An evidence‐based review of split‐thickness skin graft donor site dressings

Brown

Holloway

2018

International Wound Journal

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This evidence-based review aimed to identify and evaluate current existing evidence relating to the efficacy of dressing materials for spit-thickness skin graft donor site wounds in relation to promoting rapid healing and reducing patient pain. A comprehensive systematic search of the literature between 2006 and 2016 identified 35 publications that were included in the review. Based on the results of the review, it was found that moist wound-healing products have a clear advantage over non-moist products in the reduction of pain and increased healing rates. This review concluded that moist wound-healing products are more effective than non-moist wound-healing products in reducing pain and promoting healing in split-thickness skin graft donor site wounds. A recommendation based on this review is that further research examine the role of secondary dressing usage in donor site wound management, and the consideration of using more than one primary dressing product during the donor site wound-healing process should be undertaken.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodological and Academic Rigour Of Studiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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An evidence‐based review of split‐thickness skin graft donor site dressings

Brown

Holloway

2018

International Wound Journal

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Natural Polymer‐Based Materials for Wound Healing Applications

Ho,

Tran,

Doan

et al. 2024

Advanced NanoBiomed Research

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Skin injuries pose significant health challenges, with conditions like burns and diabetic, venous, and pressure ulcers presenting complex wound management scenarios. Effective wound care strategies for these injuries encompass a range of interventions, from simple wound dressings to bioactive materials and surgical procedures involving skin substitutes and skin grafting. This review explores the potential of natural polymers, including silk, collagen, gelatin, elastin, cellulose, chitosan, alginate, and hyaluronic acid, in wound management. Natural polymers offer several advantages, including abundance, biodegradability, and compatibility with traditional and modern material fabrication techniques, and have demonstrated safety and efficacy in clinical applications, modulating various facets of the wound healing process. Highlighting preclinical and clinical studies, along with commercial products, this review showcases the versatility and utility of natural polymers in wound management and provides insights into emerging developments, such as 3D bioprinting and stimuli‐responsive materials, which hold promise for personalized wound treatments. Additionally, we discuss the importance of the material format and morphology in engineering the next generation of wound dressings and skin substitutes, offering a pathway to optimize natural polymers for enhanced wound healing outcomes.

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Preparation of antibacterial poly(sulfobetaine methacrylate) grafted on poly(vinyl alcohol)‐formaldehyde sponges and their properties

Yang

Sha

Jiang

et al. 2018

J of Applied Polymer Sci

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Conventional wound dressings cover wound surfaces and separate them from the outer environment. However, wound sites are readily infected by some bacteria during healing. To overcome these problems, a macroporous sample is designed through the grafting polymerization of hydrophilic sulfobetaine methacrylate (SBMA) on poly(vinyl alcohol)‐formaldehyde (PVF) sponges. The as‐prepared PVF sponges have a grafting percentage of 15–50%, an average pore size of 60–90 μm, and a high porosity of 90%. This series of PVF‐g‐PSBMA sponges can absorb deionized water and saline solution at approximately 16 g·g−1 within 2 min because of their hydrophilic surface and macroporous structure. The antibacterial potential of PVF‐g‐PSBMA sponges against Escherichia coli and Staphylococcus aureus is evaluated via a shake flask test. As the grafting percentage increase from 15 to 50%, the antibacterial activities against Gram‐positive S. aureus and Gram‐negative E. coli gradually increase from 87 to 95% and from 94 to 99%, respectively. The biocompatibility of these sponges is confirmed through an in vitro cell viability assay. All of the survival rates of the bacterial cells relative to the control (100% of metabolic activity) exceed 90% as the extract ratio of PVF‐g‐PSBMA sponges increase. Thus, the as‐prepared PVF‐g‐PSBMA sponges can be an ideal wound dressing candidate. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47047.

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A prospective clinical trial comparing Biobrane ® Dressilk ® and PolyMem ® dressings on partial-thickness skin graft donor sites

Cited by 24 publications

References 37 publications

An evidence‐based review of split‐thickness skin graft donor site dressings

An evidence‐based review of split‐thickness skin graft donor site dressings

Natural Polymer‐Based Materials for Wound Healing Applications

Preparation of antibacterial poly(sulfobetaine methacrylate) grafted on poly(vinyl alcohol)‐formaldehyde sponges and their properties

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