A Position Statement on Mpox as a Sexually Transmitted Disease

Allan‐Blitz, Lao‐Tzu; Gandhi, Monica; Adamson, Paul C; Bolan, Gail; Klausner, Jeffrey D.

doi:10.1093/cid/ciac960

Cited by 49 publications

(45 citation statements)

References 38 publications

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“…This is the first Israeli case report of mpox disease in the current outbreak, and among the first in developed countries. We describe two patients, both men in their 30s who have sex with men (MSM), similar to the majority of reported cases around the world [ 5 ], reiterating the current debate of whether this new outbreak of mpox should be considered a sexually transmitted disease [ 6 , 7 ].…”

Section: Discussionsupporting

confidence: 52%

Mpox Infection in a Developed Country: A Case Report

et al. 2022

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This is the first Israeli case report of mpox (monkeypox) disease, as it is manifested in the current outbreak. This manuscript depicts two detailed patient journeys of Israeli men in their 30s who were diagnosed in recent months, depicting their symptoms, presumed exposure, and outcomes. The two cases were atypical compared to the clinical presentation prior to the current outbreak but were similar to other recent reported cases; they differed in their prodromal presentation. Importantly, both patients described that significant anxiety around the diagnosis dominated their journey while sharing that a concern is rising in the GBMSM community, a concern that should be addressed by healthcare providers.

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Section: Discussionsupporting

confidence: 52%

Mpox Infection in a Developed Country: A Case Report

et al. 2022

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“…In a study from Nigeria, among 16 Mpox cases, 8 (50%) had sex within a month before first symptom, and 62.5% had high risk behavior [22] . Thus, Mpox virus was also designated as a sexually transmitted disease [23] . In a study from the United Kingdom, rectal or perianal pain resulted in the hospitalization of 44 (28%) of 156 Mpox cases and 38 (24%) were treated with tecovirimat [24] .…”

Section: Discussionmentioning

confidence: 99%

Clinical features and outcome of human Mpox (Monkeypox) in Saudi Arabia: An observational study of travel-related cases

Assiri

Al‐Tawfiq

Jokhdar

et al. 2023

Journal of Infection and Public Health

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“…Sexual transmission was the main mode of transmission for mpox virus in the observed group and is consistent as such throughout many studies. Therefore, mpox is now considered as a sexually transmitted disease by some authors [ 26 ]. Many of the sexual contacts were reported as anonymous.…”

Section: Discussionmentioning

confidence: 99%

Mpox outbreak 2022: an overview of all cases reported to the Cologne Health Department

Kröger¹,

Lehmann²,

Treutlein³

et al. 2023

Infection

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PurposeThe worldwide mpox outbreak starting in May 2022 marks the occurrence of another previously atypical infectious disease in Europe. This study's objective was to present a comprehensive overview based on the gathered data and to illustrate the approach of the Cologne Health Department to contain the mpox outbreak. Methods In this retrospective observational study, 368 individuals reported to the Cologne Health Department as PCRpositive for mpox were included. Data were collected in structured telephone interviews and digitally processed. ResultsThe first mpox case in Cologne was recorded on May 24, 2022. The local outbreak lasted approximately 4 months and reached its peak in July. The last reported case in Cologne occurred on September 17. Transmissions mostly occurred through sexual contacts (67.4%) or other close physical contacts (4.6%) between men, but also through fomites, in the context of events or occasionally in the work environment. In 21.5% of cases, no route of infection could be determined. The mean incubation period was 8.2 days. Clinically, mpox infections usually presented with skin and/or mucosal lesions accompanied by general symptoms. In 74.8% of cases, a prodromal stage was absent. Initially, the rash often had an unspecific appearance, but in the further clinical course, it usually passed through the typical stages. Most infections resolved spontaneously under home care. In 3.5% of cases, however, inpatient hospitalisation was required. Infected persons with a previous smallpox vaccination had 0.43 times the odds of unvaccinated persons to be affected by lesions in 3 or more body regions and 0.30 times the odds to develop lesions in all 5 body regions. Previous vaccination statistically reduced the total duration of symptoms by 2.0 days. Conclusions The mpox outbreak 2022 in Cologne primarily affected men who have sex with men and have reported recent sexual encounters. The observed average incubation period was shorter than initially assumed. Mucosal involvement and associated symptoms occur in a relevant number of cases and can lead to more severe clinical courses. Previous smallpox vaccination was statistically significantly associated with milder courses of mpox. In the case of an unclear rash or symptoms suggesting mucosal involvement, mpox should be considered as a differential diagnosis. An equally rapid and wellorchestrated public health response are crucial for infection control.

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A Position Statement on Mpox as a Sexually Transmitted Disease

Cited by 49 publications

References 38 publications

Mpox Infection in a Developed Country: A Case Report

Mpox Infection in a Developed Country: A Case Report

Clinical features and outcome of human Mpox (Monkeypox) in Saudi Arabia: An observational study of travel-related cases

Mpox outbreak 2022: an overview of all cases reported to the Cologne Health Department

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