A population‐based study of the relationship between endometrial thickness and prevalence of breast mass in postmenopausal women

Abstract

Objectives To determine the relationship between endometrial thickness and the prevalence of breast mass in postmenopausal women. Methods The prevalence of breast mass was investigated in 6759 postmenopausal women (≥60 years) with different endometrial thicknesses who underwent breast and transvaginal ultrasonography from January 2015 to June 2017. Multivariable logistic regression analysis was used to obtain odds ratios and 95% confidence intervals for breast mass in postmenopausal women with increased endometrial thickness after adjusting for age, height, and body mass index. Results Compared with a baseline endometrial thickness of less than 3 mm, the prevalence of breast mass increased in patients with endometrial thickness ≥3–4.9 mm (OR 1.077; 95% CI, 0.868–1.338), ≥5–9.9 mm (OR 1.910; 95% CI, 1.189–3.067), and ≥10 mm (OR 3.546; 95% CI, 1.458–8.620) (Ptrend=0.0026). In subgroup analysis, correlations between endometrial thickness and prevalence of breast mass with malignant possibility (BI‐RADS ≥3) were similar and remained significant (Ptrend=0.035). Conclusion Postmenopausal women with endometrial thickness greater than or equal to 5 mm have a significantly increased prevalence of breast mass and breast mass with malignant possibility (BI‐RADS ≥3). Breast cancer screening for postmenopausal women with increased endometrial thickness should be given greater attention.

Relationship between the Metabolic Associated Fatty Liver Disease and Endometrial Thickness in Postmenopausal Women: A Cross-sectional Study in China

“…The ET of all participants was accurately determined by a 4-8 MHz vaginal transducer (HD11XE; Philips Medical Systems) or a 4-11 MHz transducer (Aplio 500; Canon Medical Systems), and then was routinely evaluated and recorded 33 . As transvaginal sonography, the bladder was emptied at first, patients were examined in a lithotomy position scanned with an intravaginal ultrasound probe.…”

“…The data were collected and registered in the electronic medical record system of the Quality Control Center of Health Examination in Chongqing 33 . Basic information such as age, gender, disease history, and postoperative ultrasound description was included.…”

“…Anthropometric parameters such as blood pressure, weight, height, and waist circumference were measured by allied health professionals according to standard methods. Moreover, the blood samples of metabolic components were collected after fasting for at least 8 hours and analyzed in the laboratory of the First Affiliated Hospital of Chongqing Medical University certified by the College of American Pathologists (CAP Number: 7215494) 33 . The study was approved and supervised by the Ethics Committee of The First Affiliated Hospital of Chongqing Medical University.…”

Association between ovarian and breast masses among Chinese women in Chongqing based on ultrasonography screening: A cross‐sectional study

“…Breast mass (BM) was defined as a lesion that occupies a space within the breast and often manifests as breast cyst, intraductal mass, and mixed or solid mass. 11 Final assessment of malignancy risk for breast abnormalities was provided by an experienced ultrasound examiner according to the standard of the American College of Radiology: the Breast Imaging Reporting and Data System (BI-RADS). 16 Blood flow and morphologic variables were obtained to define each ovarian mass (OM) by sonographers according to the gray-scale and color Doppler ultrasound images.…”

“…10 A breast mass is the major indicator of breast cancer in ultrasound findings and occurs in women. 11 In 2012, the China Official Breast Cancer Screening Program was conducted, and this project chose ultrasound as the initial diagnostic tool. Mammography and biopsy were applied after a diagnosis of highly suggestive malignancy or suspicious lesion.…”