A Population-based Clinical Study of Allergic and Non-allergic Asthma

Knudsen, Thomas Bøllingtoft; Thomsen, Simon Francis; Nolte, Hendrik; Backer, Vibeke

doi:10.1080/02770900802524657

Cited by 72 publications

(35 citation statements)

References 14 publications

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“…Whether the healthy worker effect, including effects at the times of entering and departing selected occupations, operates in the same way and to the same degree in females is not known. The ECRHS I population includes females aged 20–44 yrs, an age range in which there are sex-based differences in the prevalence of respiratory symptoms [20, 21]. An underestimation of occupational asthma among females has been suggested [22].…”

Section: Discussionmentioning

confidence: 99%

Healthy hire effect, job selection and inhalation exposure among young adults with asthma

Olivieri¹,

Plana²,

Radon³

et al. 2010

European Respiratory Journal

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The aim of the present study was to assess whether asthma onset prior to entering the workforce influences whether a person holds a subsequent job with asthma-related inhalation exposures. The data of 19,784 adults from the European Community Respiratory Health Survey were analysed. For each respondent, a current or previously held job was linked to a job exposure matrix assigning high, low or no exposure to dust, gases or fumes. Jobs were also categorised according to the risk of exposures related to occupational asthma. Associations between asthma and subsequent occupational exposures were assessed using logistic regression models, with a random intercept for study centre and fixed adjustment for age, sex, type of study sample and smoking status. Of the respondents, 8% (n=1,619) reported asthma with onset before completion of full-time education. This population was at decreased risk of having a job with high (odds ratio 0.79; 95% confidence interval 0.68–0.92) or low (0.91; 0.80–1.03) exposure to dust, gases or fumes. The associations were consistent across exposure types (dusts, gases or fumes) and for jobs with a high risk of occupational asthma. Adults with asthma onset prior to entering the workforce may be less likely to hold jobs involving inhalation exposures.

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Section: Discussionmentioning

confidence: 99%

Healthy hire effect, job selection and inhalation exposure among young adults with asthma

Olivieri¹,

Plana²,

Radon³

et al. 2010

European Respiratory Journal

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“…Asthma can be classified as allergic or nonallergic asthma (Beasley et al, 2000). More than 50% of adult asthma cases and 80% of childhood asthma cases are of the allergic subtype (Knudsen et al, 2009). Risk factors for allergic asthma include allergens such as house dust mites (HDM), pollen, and pet fur components (Devereux, 2006).…”

Section: A Asthma Risk Factors and Pathophysiologymentioning

confidence: 99%

Dual Role of Toll-Like Receptors in Asthma and Chronic Obstructive Pulmonary Disease

et al. 2012

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“…Nonsensitised asthma, which has a more severe clinical course in adults [25], appears to have a higher incidence in women than in men [2,26], but is found to be less often treated compared with sensitised asthma [27]. The number of prospective studies reporting sex-specific incidence rates into late adulthood is limited.…”

Section: Introductionmentioning

confidence: 99%

Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study

et al. 2015

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A higher incidence of asthma is reported in women compared with men, but evidence in later adulthood is limited. We aimed to determine the 20-year cumulative incidence of adult asthma in Switzerland and its relation to sex, taking into account age and allergic sensitisation.We assessed incidence of self-report of doctor-diagnosed asthma between 1991/1992 and 2010/2011 in 5128 subjects without asthma, aged 18-60 years at baseline. The age-related probability of asthma onset was analysed by logistic regression adjusting for potential confounders and stratified by sex and allergic sensitisation at baseline.Over 20 years, 128 (5.1%) men and 198 (7.5%) women newly reported doctor-diagnosed asthma. The adjusted odds ratio for female sex was 1.99 (95% CI 1.54-2.57) overall, 3.21 (95% CI 2.12-4.85) among nonsensitised subjects, and 1.43 (95% CI 1.02-2.02) in sensitised subjects. The probability of asthma onset decreased with increasing baseline age in women but not in men. The higher probability of new asthma in sensitised compared with nonsensitised men was unrelated to age, whereas in women it decreased with age.Asthma incidence was higher in women than in men but decreased with increasing age. The female predominance was considerably stronger in nonsensitised adults compared with those with allergic sensitisation. @ERSpublications Female predominance in new-onset adult asthma decreased with age and was more pronounced in nonsensitised subjects

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A Population-based Clinical Study of Allergic and Non-allergic Asthma

Abstract: Non-allergic asthma accounts for two in every five cases of asthma in adults and constitutes symptomatically, and in terms of lung function, a more severe form of disease than allergic asthma.

Cited by 72 publications

References 14 publications

Healthy hire effect, job selection and inhalation exposure among young adults with asthma

Healthy hire effect, job selection and inhalation exposure among young adults with asthma

Dual Role of Toll-Like Receptors in Asthma and Chronic Obstructive Pulmonary Disease

Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study

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