A polymer coated MNP scaffold for targeted drug delivery and improvement of rheumatoid arthritis

Abstract

DHAA–Fe3O4@HA as a nano-carrier was synthesized for targeted sulfasalazine delivery in specific inflammatory joint tissues with improvement in RA disease.

CuI nanoparticles supported on a novel polymer-layered double hydroxide nanocomposite: an efficient heterogeneous nanocatalyst for the synthesis of bis-N-arylsulfonamides

“…Following our recent aim of designing multifunctional catalyst; 14 in this article, we synthesized a LDH@MPS-GMA-TZ as a novel support with a thiazole moieties. After immobilization of CuI NPs, we aimed at analyzing the catalytic performance of LDH@MPS-GMA-TZ-CuI ( Scheme 1 ) for the generation of bis- N -aryl sulfonamides from the reaction of 1,3-disulfonylchloride and nitroarenes with high yields ( Scheme 2 ).…”

Aspects of high-performance and bio-acceptable magnetic nanoparticles for biomedical application

“…Moreover, the radiographic images displayed that there was no sclerosis in the animals treated with DHAA- Fe 3 O 4 @HA@SSZ. In conclusion, the tailored formulation was effective for the treatment of RA without any adverse effects [60] .…”

Preparation and characterization of copper/polysulfonamide complex immobilized on geraphene oxide as a novel catalyst for the synthesis of pyrimido[1,2‐a]benzimidazoles

“…Ethyl 4-(3-bromophenyl)-1,4-dihydro-2-methylpyrimido [1,2-a]benzimidazole-3-carboxylate (4e): melting point: 289-291 C. [12] 13 C NMR, and CHN that are given in the supporting information ( Figures S1-S30).…”

“…In addition, the nature and electronic properties of the substituents had negligible effect on the velocity and reaction yields. All products were fully characterized on the basis of their SPECTRONIC data including FT-IR, 1 H NMR, 13 C NMR, and CHN. In the next step, the reusability of GO@PSA-Cu was also evaluated in the synthesis of 4a under the optimized reaction conditions.…”

“…In continuation of our interest in exploring catalytic methodologies, [13] we have synthesized Cu-PSA complex immobilized on GO and then investigated its performance as a novel acidic nanocatalyst for the synthesis of pyrimido[1,2-a]benzimidazoles. To the best of our knowledge, there are no reports on the use of Cu-PSA complex immobilized on GO as a catalyst for the synthesis of pyrimido[1,2-a]benzimidazoles via MCRs (Figure 1).…”