A Plate Method for Quantitation of Fibrinolytic Activity.

Studies on the Mechanism of the Angiotensin Pressor Effect and of its Inhibition by Neotetrazolium

“…Ditetrazolium salts exhibit antihypertensive effects on rats with experimental renal hypertension ( 1,2). Exploration of various possible mechanisms of action revealed that neotetrazolium impairs sympathetic ganglionic transmission (3) and causes blockade of alpha-adrenergic receptors (4).…”

A Simple Device for Measuring Diameters of Fibrinolysis Zones on Fibrin Plates

“…C h r y ssa n to u and A n t o p o l [3] proposed visualization of the zones by staining the plates after incubation; but this procedure is time-consuming and makes the plates useless for further incubation. Measurements of zone diameters on fibrin plates have been carried out with calipers [2], projection machines [4], and by photoelectric methods [3]. These are similar to measure ments of growth inhibition zones of microorganisms on agar plates [5], Areas…”

“…However, commercial fibrino gen preparations frequently produce very transparent fibrin layers [2], En hancement of the fibrin concentration, which amounts normally to 0.1%, would give more opaque plates, but lowers the sensitivity of the method [2]. C h r y ssa n to u and A n t o p o l [3] proposed visualization of the zones by staining the plates after incubation; but this procedure is time-consuming and makes the plates useless for further incubation. Measurements of zone diameters on fibrin plates have been carried out with calipers [2], projection machines [4], and by photoelectric methods [3].…”