A plasmonic biosensor array by block copolymer lithography

Abstract

Highly uniform and dense, hexagonal noble metal nanoparticle arrays were achieved on large-area transparent glass substrates via scalable, parallel processing of block copolymer lithography. Exploring their localized surface plasmon resonance (LSPR) characteristics revealed that the Ag nanoparticle array displayed a UV-vis absorbance spectrum sufficiently narrow and intense for biosensing application. A highly-sensitive, label-free detection of prostate cancer specific antibody (anti-PSA) with sub-ng ml À1 level detection limit (0.1$1 ng ml À1) has been accomplished with the plasmonic nanostructure. Our approach offers a valuable route to a low-cost, manufacture-scale production of plasmonic nanostructures, potentially useful for various photonic and optoelectronic devices.

Flexible and Transferrable Self‐Assembled Nanopatterning on Chemically Modified Graphene

“…Since PDMS is frequently used for pattern masters of soft lithography, this facile transferability to PDMS offers versatile routes for the subsequent transfer onto various substrates with arbitrary chemistry and geometry. [ 42 ] The prepared metal nanoparticle array with uniform size and spatial distribution demonstrated the typical localized surface plasmon resonance (LSPR), as shown in Figure 2 f. [ 43 ] The resonance peak at 536 nm maintained its position even in a highly (20%) stretched state. This invariability of the resonance peak position is potentially benefi cial for the stable operation of fl exible and stretchable photonics in a highly deformed state.…”

High-performance nanopattern triboelectric generator by block copolymer lithography

“…Block copolymer (BCP) self-assembly offers lithographic nanotemplates for next-generation lithography as a result of the microphase separation of covalently linked incompatible polymer blocks [32][33][34]. More specifically, dense packing of self-assembled nanospheres or vertical cylinders in BCP thin films provides hexagonal nanopatterns with typical feature size ranging from 3 to 50 nm [35,36]. Owing to the inherent scalability of self-assembly principle, well-ordered hexagonal nanopatterns can be readily produced over an arbitrary large area substrate.…”

Electrochemical Biosensor Based on Nanocomposites Film of Thiol Graphene‐Thiol Chitosan/Nano Gold for the Detection of Carcinoembryonic Antigen

“…For the application of the biosensor based on AuNPs, the stability of immobilization interfaces is of importance. Currently, many methods have been developed to fabricate immobilization interfaces based on AuNPs, for instance, S-Au and NH-Au chemical bonding [30,31], and block copolymer matrices [32,33]. Nevertheless, these methods still have certain disadvantages limiting their application.…”