A pixelated silicon telescope for solid state microdosimetry

Agosteo, S.; Fallica, P. G.; Fazzi, A.; Introini, M.V.; Pola, A.; Valvo, G.

doi:10.1016/j.radmeas.2007.12.053

Cited by 42 publications

(58 citation statements)

References 4 publications

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“…The detector measures the energy deposited in a sensitive volume of ~10 µm 3 , similar to the dimensions of a biological cell. A comparison with TEPC results, obtained at a fast neutron therapy facility agree well in the high-LET region (> 2 keV µm -1 A new monolithic silicon telescope, suitable for both microdosimetry and particle-identification-based approaches of dose assessment, has been developed by Cornelius, Agosteo and colleagues [25][26][27][28][29]. The telescope consists of a ∆E and E stage, which share a common p+ anode.…”

Section: Recent Developmentsmentioning

confidence: 80%

State of the Art in Electronic Dosemeters for Neutrons

Luszik-Bhadra¹

2011

AIP Conference Proceedings

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Articles you may be interested in 3D printer generated thorax phantom with mobile tumor for radiation dosimetry Rev. Sci. Instrum. 86, 074301 (2015); Abstract. The paper presents an overview of electronic personal dosemeters for neutrons in mixed neutron/photon fields. The energy response of commercially available electronic dosemeters in quasi-monoenergetic neutron fields and their performance in working places is discussed. The response curves are extended to high-energy neutrons up to 100 MeV, new prototype dosemeters are described and discussed especially for use at high-energy accelerators and in space.Electronic personal dosemeters for neutrons are much less developed than those for photon and beta radiation fields. After an introduction on quantities measured in personal dosimetry, a short overview of the performance of electronic dosemeters for photons and electrons is given. This is followed by a description of the general problems for the development of neutron dosemeters, i.e. the huge range of neutron energies encountered in workplace fields, the limited number of nuclear reactions available for detecting these neutrons and the problems involved in the discrimination of photon-induced signals in mixed neutron-photon radiation fields.First, the performance of passive personal neutron dosemeters is described for the two main detection methods in routine use, i.e. that of TLD-Albedo dosemeters and nuclear track dosemeters. This is followed by the description of the performance of commercially available electronic neutron dosemeters, most of them based on silicon detectors, and some prototype dosemeters, based on special silicon detectors, bubble detectors, direct ion storage (DIS) detectors and tissue equivalent counters (TEPCs). The results of measurements in calibration fields and in workplace fields of the nuclear industry are presented. In addition, the existing neutron energy responses of dosemeters are updated to higher energies, up to about 100 MeV, in order to estimate the readings of these dosemeters behind the heavy shielding of high-energy accelerators, i.e. for use in ion therapy.At the end, a short outlook is given of the development of electronic personal dosemeters for astronauts. The radiation field in space is even much more complex since it includes not only neutrons and photons, but also ions and electrons and dose equivalent spectra extend to even higher energies.

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Section: Recent Developmentsmentioning

confidence: 80%

State of the Art in Electronic Dosemeters for Neutrons

Luszik-Bhadra¹

2011

AIP Conference Proceedings

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“…To validate the operation of the micro-calorimeters and, in the future, to investigate the assumption made in ionisation-based microdosimeters that there is a proportionality between ionisation and energy deposition, comparisons will be performed with a silicon-microtelescope [12,13] and a mini-TEPC [14] that both have been tested extensively in proton beams [15,16].…”

Section: Microdosimetrymentioning

confidence: 99%

Biologically Weighted Quantities in Radiotherapy: an EMRP Joint Research Project

Rabus

Hilgers

Sharpe

et al. 2014

EPJ Web of Conferences

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Abstract. Funded within the European Metrology Research Programme (EMRP) [1], the joint research project "Biologically weighted quantities in radiotherapy" (BioQuaRT) [2] aims to develop measurement and simulation techniques for determining the physical properties of ionising particle tracks on different length scales (about 2 nm to 10 μm), and to investigate the correlation of these track structure characteristics with the biological effects of radiation at the cellular level. Work package 1 develops micro-calorimeter prototypes for the direct measurement of lineal energy and will characterise their response for different ion beams by experiment and modelling. Work package 2 develops techniques to measure particle track structure on different length scales in the nanometre range as well as a measurement device integrating a silicon microdosimeter and a nanodosimeter. Work package 3 investigates the indirect effects of radiation based on probes for quantifying particular radical and reactive oxygen species (ROS). Work package 4 focuses on the biological aspects of radiation damage and will produce data on initial DNA damage and late effects for radiotherapy beams of different qualities. Work package 5 provides evaluated data sets of DNA cross-sections and develops a multi-scale model to address microscopic and nanometric track structure properties. The project consortium includes three linked researchers holding so-called Researcher Excellence Grants, who carry out ancillary investigations such as developing and benchmarking a new biophysical model for induction of early radiation damage and developing methods for the translation of quantities derived from particle track structure to clinical applications in ion beam therapy.

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“…This comparison verifies the theoretical feasibility of absolute beam dosimetry. Fig.9: Dose-mean lineal energy measured at different neutron energies En with the segmented telescope and by a spherical TEPC simulating different diameter sites [9] The second term, the mean chord length, is computed on a shape equivalence basis [7]. A comparison between the dosedistribution of lineal energy measured by the illilE silicon microdosimeter (red curve) and the dose-distribution of lineal…”

Section: L1e Stage E Stagementioning

confidence: 99%

“…Comparison between the dose-distribution of lineal energy measured by the segmented telescope coupled to a polyethylene converter (red curve) and with a cylindrical TEPC simulating a site 2.7 pm in diameter and height (black curve)[7] .…”

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confidence: 99%

Radiation detectors based on silicon monolithic telescope in medical applications

Fazzi

Agosteo

Pola

et al. 2008

2008 IEEE Nuclear Science Symposium Conference Record

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DitTerent silicon detectors have been designed and fabricated based on the silicon monolithic telescope concept. The surface vertical diode, the AE stage, is only about 2 pm thick and shows very good charge collection properties. Circular anodes with a diameter of about 10 pm allow to obtain cylindrical sensitive volumes of micrometric size. This micrometric diode has been proposed as a silicon microdosimeter with the proper corrections for the chord distribution and the tissue equivalence. The lineal energy spectrum has been successfully compared with TEPC spectra and the dose-mean lineal energy with data from literature. The present lower limit is about 10 keV pm-1 fixed by the electronic noise.A similar detector, with an active area of about 1 mm 2 and lower limit 4 keV pm-I, has been proposed for hadrontherapy applications and preliminarily tested on 100 MeV clinical proton beam of LLUMC. The microdosimeter operating range, presently limited to medium-and high-LET events, can etTectively characterize the radiation quality across the Bragg peak and in the distal region.Recently, larger detectors have been irradiated coupled to a borate biological sample in the thermal neutron field of the LENA reactor in order to estimate the boron concentration for BNCT applications.

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A pixelated silicon telescope for solid state microdosimetry

Cited by 42 publications

References 4 publications

State of the Art in Electronic Dosemeters for Neutrons

State of the Art in Electronic Dosemeters for Neutrons

Biologically Weighted Quantities in Radiotherapy: an EMRP Joint Research Project

Radiation detectors based on silicon monolithic telescope in medical applications

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