A pilot study on the effects of transcutaneous and transmucosal laser irradiation on blood pressure, glucose and cholesterol in women

Abstract

The present pilot study had the objective to determine the effects of transcutaneous and transmucosal laser irradiation on arterial blood pressure (ABP), glucose (Glu) triglycerides (Tg), total cholesterol (Ch), high-density level cholesterol (HDL) and low-density cholesterol (LDL) immediately after treatment (T0) and after 30 (T30) and 60 (T60) days. Patients (n ¼ 36) were selected and randomly distributed into 6 groups (n ¼ 6/group; [G1] negative control, [G2] radial artery transcutaneous laser irradiation [G3] radial artery transcutaneous irradiation, [G4] transmucosal sublingual irradiation, [G5] transmucosal intra-nasal irradiation and [G6] extended radial artery transcutaneous irradiation). Blood exams were performed at T0, T30 and T60. Systolic and diastolic pressure results have indicated that patients' pressures ranged from 90 mmHg (P22, T30, G4) to 189 mmHg (P16, T0, G3) and 54 mmHg (P21, T60, G4) to 175 mmHg (P16, T30, G3). Levels of Glu at T30 and T60 varied from 5.53% (G1) to -5.78% (G6) and 1.21 (G2) to -8.69 (G6), respectively. Data was statistically assessed for normality and homogeneity of variances using the F-statistic and Bartlett's tests. Significant differences were determined using One-Way ANOVA and Fischer post hoc tests. Results indicated that treatments investigated can be safely used as an adjunct method to regulate blood pressure, glucose, triglycerides and cholesterol.

Effect of Photo-Bio modulation on lipid profile in Patients with type 2 diabetes mellitus: A Randomized Clinical Trial

“…In a pilot investigation, the impact of systemic trans-mucosal and/or transcutaneous laser therapy on lipid profiles (TC, HDL, LDL, and TG) and blood sugar at 30 and 60 days was examined. The findings demonstrated the safety of using ILIB for controlling lipid profile and blood glucose, regardless of the irradiation route (either trans mucosal or transcutaneous) (27), Results therefore agree with us and with previous reports (12,19).…”

The effects of transcranial laser photobiomodulation and neuromuscular electrical stimulation in the treatment of post‐stroke dysfunctions

“…Moreover, a systemic effect mediated by blood circulation [55] may also occur with the transcranial photobiomodulation [56]. In this context, the effects of photobiomodulation on systemic inflammation, include a decrease in production of reactive oxygen and reactive nitrogen species which lead to an increase of antioxidant activity, improving brain function [56].…”

Associação de diferentes abordagens da laserterapia de baixa potência no tratamento da deiscência cirúrgica de artroplastia do joelho

“…Um deles, sozinho, ajuda a resolver o problema, porém necessita do sinergismo da outra terapia para ser mais eficaz. O emprego da FBM é excelente, mas pode ser muito melhor se houver oxigenação dos tecidos, ausência de infecção e condições corporais adequadas (Lizarelli, 2018).…”

“…Utilizando doses baixas e moderadas, é possível irradiar, localmente, lesões e áreas com baixa oxigenação e acúmulo de toxinas. Aplicando altas doses, é possível irradiar sistemicamente o paciente, melhorando suas respostas fisiológicas em todo o organismo e, auxiliando, indiretamente, o tratamento das áreas traumatizadas ou com lesões, e, finalmente, também com doses mais altas, o emprego desses lasers, ainda que apresentem baixas potências (até 100mW), torna-se possível promover uma fotoativação de drogas fotossensíveis, previamente incorporadas nos tecidos-alvo, resultando numa reação fotodinâmica, e em controle microbiológico (terapia fotodinâmica antimicrobiana) (Lizarelli., 2018).…”