Effect of Photo-Bio modulation on lipid profile in Patients with type 2 diabetes mellitus: A Randomized Clinical Trial

doi:10.47750/jptcp.2023.30.03.010

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JPTCP 2023

DOI: 10.47750/jptcp.2023.30.03.010

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Effect of Photo-Bio modulation on lipid profile in Patients with type 2 diabetes mellitus: A Randomized Clinical Trial

Abstract: Objective: to investigate the low level laser therapy (LLLT) efficiency by using laser watch as an adjunctive therapy of dyslipidemia in type 2 diabetes mellitus (T2DM) patients. Methods:The study included sixty adult patients with diabetic dyslipidemia of both gender. They were split into two groups. Study group received anti diabetic drugs along with laser watch therapy (3 sessions /week for 12 weeks), while control group received only anti diabetic drugs. Blood sugar (FBS, 2HPP and HbA1C) and lipid panel (T… Show more

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2024

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Non-invasive laser therapy effect on lipid profile and renal function in metabolic syndrome: randomized control trial

Abd El-sabour,

Badr,

Attia

et al. 2024

Bulletin of Rehabilitation Medicine

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INTRODUCTION. Metabolic syndrome (MetS) represents an assortment of interconnected metabolic risk factors, particularly central obesity, dyslipidemia, and hyperglycemia. These variables have a detrimental impact on renal function and contribute to increased mortality. This timeline necessitates a prompt approach that enables the deployment of safe and non-intrusive therapeutic equipment in conjunction with therapy for MetS patients. Accordingly, we aim to investigate whether using a low-level laser (LLL) watch device as a non-invasive instrument enhances multiple metabolic parameters, so it may be a practical therapeutic approach for managing metabolic disorders. AIM. To investigate the effect of non-invasive laser therapy on parameters of lipid profile and renal function in patients with metabolic syndrome. MATERIALS AND METHODS. This study enrolled 40 MetS patients of both genders aged 45–65 years. The study group received a 12-week treatment consisting of oral hypoglycemic medication and LLL therapy (LLLT), which involved three weekly sessions performed in the morning, targeting the wrist area using a continual output diode laser (skin contact mode, maximum power: 0.005 W, beam spot area: 0.03 cm2, energy density: 288 J/cm3, and radiation time: 1800 s). The control group only received hypoglycemia medications. Laboratory lipid profile and renal function measurements were conducted prior to and following the trial. RESULTS. Following a 12-week laser watch therapy, the results revealed a significant decline in total cholesterol (TC), triglycerides (TG), and low-density lipoprotein (LDL) levels and an increase in high-density lipoprotein (HDL) levels, which was slightly improved in the control (p 0.00). Moreover, glomerular filtration rate (GFR) and creatinine levels were significantly improved, while the control group did not experience any significant improvement (p 0.5). DISCUSSION. Combining non-invasive laser therapy with hypoglycemic medications significantly improved the lipid profile in patients with MetS; however, kidney function, like GFR and creatinine levels, was enhanced. Furthermore, lower TC and TG levels might be due to the reduction of glycation and promoted LDL receptors which increased LDL catabolism. CONCLUSION. Non-invasive laser therapy enhances lipid profile and renal function in MetS patients. Furthermore, the control group had a minimal effect on the lipid profile and no effect on renal function.

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Non-invasive laser therapy effect on lipid profile and renal function in metabolic syndrome: randomized control trial

Abd El-sabour,

Badr,

Attia

et al. 2024

Bulletin of Rehabilitation Medicine

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show abstract

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Effect of Photo-Bio modulation on lipid profile in Patients with type 2 diabetes mellitus: A Randomized Clinical Trial

Cited by 1 publication

References 29 publications

Non-invasive laser therapy effect on lipid profile and renal function in metabolic syndrome: randomized control trial

Non-invasive laser therapy effect on lipid profile and renal function in metabolic syndrome: randomized control trial

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