A physiological approach to fluid and electrolyte therapy in the horse

Rose, R. J.

doi:10.1111/j.2042-3306.1981.tb03439.x

Cited by 49 publications

(34 citation statements)

References 19 publications

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“…Observou-se que a partir do T12t a motilidade começou a aumentar nos animais de todos os grupos. Nos animais da HET, esse evento possivelmente foi ocasionado pelo estímulo do reflexo gastrocólico, como foi citado por Rose (1981), Clark (1990), Freeman et al (1992) e McGinness et al (1996); nos animais do grupo SEN, provavelmente pela ação procinética da sene, como descrito por Witte (1993); e nos do grupo IV, o que, segundo Ribeiro Filho et al (2007), pode ter sido ocasionado pela hiperhidratação parenteral, que é eficiente em aumentar a motilidade intestinal quando há compactação (Tabela 1). Como citado anteriormente, não se constatou atonia intestinal nos equinos do presente estudo, o que pode ser ressaltado como aspecto positivo do modelo de indução de compactação do cólon maior.…”

Section: Resultsunclassified

Tratamentos da compactação experimental do cólon maior de equinos com hidratação enteral, intravenosa e sene (Cassia augustifolia Vahl)

2012

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Treatment of experimental large colon impaction in horses: enteral and parenteral fluid therapy and senna (Cassia augustifolia Vahl)The objective of this study was to investigate the effect of senna associated with intravenous fluid therapy (SEN), isotonic polionic enteral solution (PE) and intravenous fluid therapy (IV) alone in the treatment of experimental large colon impaction in horses. Fifteen horses with experimentally induced colon impaction were divided in three groups: Group PE received the isotonic polionic enteral solution (8 mL kg -1 h -1 , during 48 h); Group SEN received senna (20 mg kg -1 , two doses with 24 h interval) + Ringer lactate i.v. (10 mL kg -1 h -1 12 h -1 , for two days); and Group IV received Ringer lactate i.v. (16 mL kg -1 h -1 12 h -1 , for two days). The treatment protocol of group PE increased fecal hydration and helped remove impaction faster; however, prolonged intestinal hypomotility were observed. The treatment protocol SEN normalized the intestinal motility faster; however the time required to remove impaction was higher and caused higher increase in abdominal distention and pain, as well as less capacity to revert dehydration. The treatment used for group O objetivo deste estudo foi investigar a ação da hidratação enteral (HET), da hidratação intravenosa (IV) e da sene, associada à hidratação intravenosa (SEN), no tratamento da compactação do cólon maior, em equinos. Foram utilizados 15 animais, divididos em três grupos de cinco, cada. Os animais eram portadores de compactação do cólon maior, induzida experimentalmente. O grupo HET recebeu solução isotônica poliônica enteral (8 mL kg -1 h -1 , durante 48 horas); o grupo SEN foi tratado com sene (20 mg kg -1 , duas doses de 24/24 h), mais Ringer lactato i.v. (10 mL kg -1 h -1 12h -1 , durante dois dias) e ao grupo IV foi administrado Ringer lactato i.v. (16 mL kg -1 h -1 12h -1 , durante dois dias). O tratamento HET ocasionou maior amolecimento das fezes e desfez a compactação em menor tempo. Entretanto, foi observada hipomotilidade intestinal mais prolongada. O tratamento SEN normalizou mais rapidamente a motilidade intestinal, porém o tempo necessário para desfazer a compactação foi maior. Além disso, ocasionou o maior aumento na distensão abdominal e no grau da dor, assim como a menor capacidade para reverter a desidratação. O tratamento do grupo IV debelou a compactação, igualmente ao HET, e a hipomotilidade intestinal, em menor tempo, mas foi o que menos amoleceu as fezes. Concluiu-se que os tratamentos IV e HET foram os mais eficientes na terapia da compactação, induzida no cólon maior, em equinos. O grupo SEN foi eficiente, porém, foi o que apresentou os efeitos adversos mais importantes.

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Section: Resultsunclassified

Tratamentos da compactação experimental do cólon maior de equinos com hidratação enteral, intravenosa e sene (Cassia augustifolia Vahl)

2012

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“…Weniger als 1.5% des gesamten Kaliums im Körper findet sich in der Extrazellulärflüssigkeit (Rose 1990). Plasma Kaliumkonzentrationen sagen demnach wenig über den Kaliumhaushalt des Körpers aus (Rose 1981). Über die tägliche Futterration nehmen Pferde viel Kalium auf (Tasker 1967, Groenendyk et al 1988, welches hauptsächlich über die Nieren wieder ausgeschieden wird (Johnson 1998, Tasker 1967.…”

Section: Elektrolytverteilung (Abb 2)unclassified

Intravenous fluid therapy in the horse

Wüger¹,

Straub²,

Gerber³

2006

PHK

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ZusammenfassungDie intravenöse Flüssigkeitsgabe ist ein wichtiger Bestandteil in der heutigen Pferdemedizin. Ein 500 kg schweres Pferd hat einen Körper-wasseranteil von 300-350 Liter, davon befinden sich 100 Liter im Extrazellulärraum und 200 Liter im Intrazellulärraum. Der Erhaltungswert eines adulten Pferdes beträgt 60 ml/kg KGW/Tag. Große Flüssigkeitsverluste können besonders bei starkem Durchfall, bei Sequestration von Flüssigkeit in den Gastrointestinaltrakt und bei übermäßiger Schweißproduktion entstehen. Änderungen im Elektrolythaushalt sind meistens eine Folge gestörter Aufnahme, Resorption oder Verlusten von Elektrolyten, welche am schnellsten und zuverlässigsten mit der renalen Elektrolyt/Kreatininexkretion, ("fractional excretion" (FE)), erfasst werden. Ungleichgewichte im Säuren-Basen Haushalt werden vor allem bei akuter Diarrhoe, starker Anstrengung, bei Schockzuständen und Kolik beobachtet. Bei der Therapie eines Schock-Intensivpatienten ist eine möglichst schnelle Wiederherstellung des Flüssigkeitsvolumens zur Sicherung der normalen Körperfunktion wichtig. Dazu wird am effektivsten hypertone kristalloide Infusionslösung (NaCl 7.5%) in einer Dosierung von 4 ml/kg KGW gegeben gefolgt von isotoner kristalloider Infusionslösung in einer Dosierung von initial bis zu 90 ml/kg KGW. Ebenfalls können natürliche oder künstliche kolloide Lösungen (z.B. frisches oder gefrorenes Plasma, Hydroxyethylstärke) zusammen mit isotoner kristalloider Infusionslösung verabreicht werden. Nach erfolgter Stabilisierung ist die Umstellung auf eine Erhaltungslösung mit weniger Natrium, aber mit Zusätzen von Kalium, Kalzium, Magnesium und Glukose, in Abhängigkeit von klinischen und labordiagnostischen Parametern, sinnvoll. Schlüsselwörter: Intensivmedizin, Elektrolyte, Wasserhaushalt, Infusionstherapie Intravenous fluid therapy in the horseIntravenous fluid therapy is an integral part of the treatment of the critically ill equine patient. A 500 kg horse has total body water content of approximately 300-350 litres, divided into two body water compartments, the intracellular fluid compartment, which contains approximately 200 litres of total body water, and the extracellular fluid compartment with approximately 100 litres of total body water. Mean values of daily total water intake are estimated at 60 ml/kg body weight/day in an adult horse. Fluid losses occur especially in horses with acute diarrhea, with sequestration of fluid in the gastrointestinal tract and with excessive sweating. Changes in electrolyte balance are usually a result of inadequate intake or excessive loss. Calculation of urine fractional excretion allows for early and sensitive detection of electrolyte disturbances. Acid-base imbalances are observed, for example, in horses with acute diarrhea, with all different kinds of shock, with colic and with exhaustion. Prompt administration of fluids is important for maintaining vital functions in critically ill patients. Hypertonic crystalloids (NaCl 7.5%) in a dosage of 4 ml/kg body weight followed by isotonic crys...

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“…Among the solutions for parenteral use in horses, lactated Ringer's and 0.9% sodium chloride are probably the most common solutions used worldwide. Lactated Ringer's solution (LR) has a polyionic composition similar to plasma, and is therefore commonly administered for general use (ROSE, 1981). LR has a slight alkalinizing effect in blood, which has already been described in horses (RIBEIRO FILHO et al, 2007) and dogs (RIBEIRO FILHO et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…III Departamento de Clínica e Cirurgia Veterinárias, Universidade Federal de Minas Gerais (UFMG), Minas Gerais, MG, Brasil. sodium chloride solution can lead to hyperchloremic metabolic acidosis and has been indicated to most animals suffering from dehydration associated with sodium and chloride loss (ROSE, 1981;MATHEWS, 1998).…”

Section: Introductionmentioning

confidence: 99%