A photoelectrochemical sensor through quenching of photoinduced electrons based on a G-quadruplex/hemin complex

Abstract

A novel label-free photoelectrochemical sensor was fabricated for the detection of K+ based on the electron withdrawal effect of hemin. The decreasing photocurrent from photoinduced electron transfer by a G-quadruplex/hemin complex was utilized.

Photoelectrochemical detection of metal ions

“…13, the decreasing photocurrent from photoinduced electron transfer by the formation of a G-quadruplex/hemin complex in the presence of K + was utilized as a sensing signal for label-free PEC detection of K + , and a linear relationship of photocurrent intensity versus K + concentration from 0.5 to 10 mM was obtained. 84…”

A novel, label-free fluorescent aptasensor for cocaine detection based on a G-quadruplex and ruthenium polypyridyl complex molecular light switch

“…In addition, it is reported that the G-quadruplex can be stabilized by alkali metal cations, especially potassium ions. 15 Thus, the composition of reaction buffer should also be evaluated.…”

“…3A and B. This might be due to the fact that K + could effectively stabilize G-rich oligonucleotides 15 and induce an extremely stable G-quadruplex structure when the number of G-bases is more than three, and it cannot dissociate into separate DNA strands even in the presence of target cocaine. When the G-base amount was more than ve, Gquadruplexes in buffer 1 were also very stable upon target binding.…”