A Phase II Comparative Study of Gross Tumor Volume Definition With or Without PET/CT Fusion in Dosimetric Planning for Non–Small-Cell Lung Cancer (NSCLC): Primary Analysis of Radiation Therapy Oncology Group (RTOG) 0515

Bradley, Jeffrey D.; Bae, Kyounghwa; Choi, Noah C.; Forster, Ken; Siegel, Barry A.; Brunetti, Jacqueline; Purdy, James A.; Faria, Sergio; Vu, Toni; Thorstad, Wade L.; Choy, Hak

doi:10.1016/j.ijrobp.2010.09.033

Cited by 93 publications

(54 citation statements)

References 18 publications

(5 reference statements)

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“…In RTOG 0515 the mean GTV for PET/CT was 86.2 cm3 vs. 98.7 cm3 for CT alone with a 12.5 % decrease in GTV with PET/CT [13]. Our results suggest greater variability in position, rather than size.…”

Section: Discussionmentioning

confidence: 53%

A Prospective Study to Determine Inter-observer Variability of Gross Tumor Volume with [18F] Fludeoxyglucose-PET/CT Compared to CT Alone in Stage III Non-Small Cell Lung Cancer Using Three-Dimensional Analysis

Peterson¹,

Ahmed²,

Rivest³

et al. 2013

Cureus

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Section: Discussionmentioning

confidence: 53%

A Prospective Study to Determine Inter-observer Variability of Gross Tumor Volume with [18F] Fludeoxyglucose-PET/CT Compared to CT Alone in Stage III Non-Small Cell Lung Cancer Using Three-Dimensional Analysis

Peterson¹,

Ahmed²,

Rivest³

et al. 2013

Cureus

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“…PET/CT–CT fusion is usually suitable for lung cancer radiotherapy planning 1. But image fusion for biopsy, in our view, is not a common technique.…”

Section: Descriptionmentioning

confidence: 98%

CT and PET/CT fusion for lung cancer biopsy planning

Cherkashin¹,

Aniskhin²,

Berezina³

et al. 2017

BMJ Case Reports

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“…The elective nodal failure rate for GTVs derived from PET/ CT was low, supporting the RTOG standard of limiting the target volume to the primary tumor and involved nodes. 83 …”

Section: Pet/computed Tomography Planning For Lung Cancermentioning

confidence: 99%

Radiotherapy Planning

Truong

Kovalchuk

2015

PET Clinics

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Incorporation of PET/computed tomography (CT) in radiotherapy planning plays a critical role in assisting gross tumor volume delineation for radiotherapy planning and delivery. As radiotherapy techniques evolve to become more conformal with the increasing use of intensity-modulated radiotherapy and stereotactic body radiotherapy, whereby sharp dose gradients exist between the target and adjacent normal tissue, accurate contouring of tumor targets is vital for the success of radiotherapy to achieve cure and locoregional control. This article outlines the integration of PET/CT into radiotherapy planning for head and neck, lung, and other solid tumors.

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A Phase II Comparative Study of Gross Tumor Volume Definition With or Without PET/CT Fusion in Dosimetric Planning for Non–Small-Cell Lung Cancer (NSCLC): Primary Analysis of Radiation Therapy Oncology Group (RTOG) 0515

Abstract: Background-RTOG 0515 is a Phase II prospective trial designed to quantify the impact of PET/CT compared to CT alone on radiation treatment plans (RTPs) and to determine the rate of elective nodal failure for PET/CT derived volumes.

Cited by 93 publications

References 18 publications

A Prospective Study to Determine Inter-observer Variability of Gross Tumor Volume with [18F] Fludeoxyglucose-PET/CT Compared to CT Alone in Stage III Non-Small Cell Lung Cancer Using Three-Dimensional Analysis

A Prospective Study to Determine Inter-observer Variability of Gross Tumor Volume with [18F] Fludeoxyglucose-PET/CT Compared to CT Alone in Stage III Non-Small Cell Lung Cancer Using Three-Dimensional Analysis

CT and PET/CT fusion for lung cancer biopsy planning

Radiotherapy Planning

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