A pharmacological validation of radiotelemetry in conscious, freely moving rats

A novel automated method for measuring the effect of analgesics on formalin-evoked licking behavior in rats

“…Most methods focus on the automated measurement of rotational behavior (Barber et al, 1973;Bonatz et al, 1987;Greenstein and Glick, 1975;Hudson et al, 1993;Rozas et al, 1997;Torello et al, 1983;Ungerstedt and Arbuthnott, 1970;Walsh and Silbergeld, 1979) as well as horizontal movement (motor activity) with the use of photo beams (Beninger et al, 1985;Clarke et al, 1985;Kulmala et al, 1987;Robles, 1990;Soulairac and Charpentier, 1966;Young et al, 1993), video-tracking (Dielenberg et al, 2006;Eden et al, 2005;Keller et al, 2000;Kernan et al, 1987;Nickolson, 1981;Noldus et al, 2001;Pinhasov et al, 2005;Shinba et al, 1996;Tanger et al, 1978) or telemetry (Deveney et al, 1998). With regard to the formalin test, several approaches have been attempted for automated measurement.…”

On the importance of telemetric temperature sensor location during intraperitoneal implantation in rats

“…Although displacements of the sensor within the IP cavity are very limited; due to adhesions occurring with the device, it is usually fixed within the abdomen. 21,22 Furthermore, a mean absolute difference of AE0.17 C has previously been reported between nonattached sensors implanted intraperitoneally in rats. 23 The authors hypothesized that the rodents' activities such as food/water intake and locomotion/sleep could affect each sensor differently depending on its location.…”

Implantation and Monitoring of a Novel Telemetry Unit in the Syrian Golden Hamster Model

“…Evaluation of the transmitter from both surgical and data collection perspectives indicates that the HD-X11 transmitter can be a useful tool to researchers in a wide range of scientific and medical fields. investment alternative while maintaining high-quality data measurement in a validated system [2,5].…”

“…Evaluation of the transmitter from both surgical and data collection perspectives indicates that the HD-X11 transmitter can be a useful tool to researchers in a wide range of scientific and medical fields. investment alternative while maintaining high-quality data measurement in a validated system [2,5].Small animal models are useful in laboratory research as a relatively inexpensive alternative to large animals and are used in a diverse range of disciplines including safety, biopharmaceutical, and disease research [2,[6][7][8]. Radiotelemetry permits detection of physiological signals through implanted transmitters that broadcast analog frequency signals to a closeproximity receiver [2].…”