A pH-sensitive coordination polymer network-based nanoplatform for magnetic resonance imaging-guided cancer chemo-photothermal synergistic therapy

Zhang, Cuiting; Li, Jing; Yang, Chenxi; Gong, Siman; Jiang, Hu‐Lin; Sun, Minjie; Qian, Chenggen

doi:10.1016/j.nano.2019.102071

Cited by 38 publications

(25 citation statements)

References 54 publications

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“…24,25 It can gradually degrade in response to the weakly acidic tumor microenvironment (TME), 26 and be effectively excreted from the body without causing long-term retention and toxicity problems. 27 Until now, many examples of various drugs have been successfully delivered by the Fe-GA coordination polymer. 28 However, most reported drug loadings by the Fe-GA coordination polymer relied on surface adsorption between the drug molecules and Fe-GA, resulting in unsatisfactory drug loading amount.…”

Section: Introductionmentioning

confidence: 99%

pH-responsive hollow Fe–gallic acid coordination polymer for multimodal synergistic-therapy and MRI of cancer

Liu¹,

Li²,

Jiang³

et al. 2022

Nanoscale Adv.

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Section: Introductionmentioning

confidence: 99%

pH-responsive hollow Fe–gallic acid coordination polymer for multimodal synergistic-therapy and MRI of cancer

Liu¹,

Li²,

Jiang³

et al. 2022

Nanoscale Adv.

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“…The drug Gallic acid was able to be released in acidic pH as tumor environment inducing apoptosis. The study revealed that the nanonetwork due to its extraordinary photostability and photothermal therapy capacity is quite promising as nanotheranostic [221] . Furthermore, paclitaxel was loaded into nanocapsules comprised from PLGA-PEG and perfluorooctyl bromide (PFOB) as nanotheranostic agents.…”

Section: Nanotheranostics Categories According To Their Chemical Natumentioning

confidence: 99%

Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities

Sıafaka

Okur

Karantas

et al. 2021

Asian Journal of Pharmaceutical Sciences

121

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In the last decade, the use of nanotheranostics as emerging diagnostic and therapeutic tools for various diseases, especially cancer, is held great attention. Up to date, several approaches have been employed in order to develop smart nanotheranostics, which combine bioactive targeting on specific tissues as well as diagnostic properties. The nanotheranostics can deliver therapeutic agents by concomitantly monitor the therapy response in real-time. Consequently, the possibility of over- or under-dosing is decreased. Various non-invasive imaging techniques have been used to quantitatively monitor the drug delivery processes. Radiolabeling of nanomaterials is widely used as powerful diagnostic approach on nuclear medicine imaging. In fact, various radiolabeled nanomaterials have been designed and developed for imaging tumors and other lesions due to their efficient characteristics. Inorganic nanoparticles as gold, silver, silica based nanomaterials or organic nanoparticles as polymers, carbon based nanomaterials, liposomes have been reported as multifunctional nanotheranostics. In this review, the imaging modalities according to their use in various diseases are summarized, providing special details for radiolabeling. In further, the most current nanotheranostics categorized via the used nanomaterials are also summed up. To conclude, this review can be beneficial for medical and pharmaceutical society as well as material scientists who work in the field of nanotheranostics since they can use this research as guide for producing newer and more efficient nanotheranostics.

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“…Noninvasive magnetic fields in conjunction with hybrid superparamagnetic nanoparticles offers spatial and temporal controlled stimuli-responsive drug delivery [23]. Interestingly, HNPs based cancer theranostics not only provide theranostic agent to assist tumor imaging and therapy, but also give an avenue to develop theranostic agent combined MRI, chemotherapy, and PTT in single platform to combat cancer in advanced stage [24,25]. As an alternative to companion radio imaging and thermal therapy, NIR-II imaging combined with the noninvasive focused ultrasound (FUS) is developed to detect and treat the orthotopic brain tumor [26].…”

Section: Hybrid Nanoplatforms Advancing Cancer Theranosticsmentioning

confidence: 99%

Comprehensive approach of hybrid nanoplatforms in drug delivery and theranostics to combat cancer

Thorat

Townley

Patil

et al. 2020

Drug Discovery Today

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To date, various chemically and biosynthesized nanoparticles, or hybrid nano systems, have been developed under the umbrella of nanomedicine. These may be introduced into the body either orally, nasally, intratumourally or intravenously . Successfully translating hybrid nanoplatforms from preclinical proof-of-concept to therapeutic value in the clinic is challenging. Having made significant advances with drug-delivery technologies, we must learn from other areas of oncology drug development, where patient stratification and target-driven design have improved patient outcomes. This review aims to identify gaps in our understanding of the current strengths of nanomedicine platforms in drug delivery and cancer theranostics. We report on the current approaches of nanomedicine at preclinical and clinical stages.

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A pH-sensitive coordination polymer network-based nanoplatform for magnetic resonance imaging-guided cancer chemo-photothermal synergistic therapy

Cited by 38 publications

References 54 publications

pH-responsive hollow Fe–gallic acid coordination polymer for multimodal synergistic-therapy and MRI of cancer

pH-responsive hollow Fe–gallic acid coordination polymer for multimodal synergistic-therapy and MRI of cancer

Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities

Comprehensive approach of hybrid nanoplatforms in drug delivery and theranostics to combat cancer

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