A pH-responsive hydrophilic controlled release system based on ZIF-8 for self-healing anticorrosion application

Yang, Congren; Xu, Wenjie; Meng, Xin; Shi, Xinlong; Shao, Lang; Zeng, Xiangliang; Yang, Zhenfei; Li, Sijian; Liu, Yutang; Xia, Xinnian

doi:10.1016/j.cej.2021.128985

Cited by 108 publications

(37 citation statements)

References 50 publications

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“…The Zn 2p spectrum showed the binding energies of 2p 3/2 and 2p 1/2 (Figure B). Compared with ZIF-8 and GZ, the binding energies of GZB show negative shifts (from 1021.6 to 1021.8 eV and from 1044.6 to 1044.8 eV), which may be due to the weak binding between Zn in ZIF-8 and BTA or coordination . The C 1s peaks of GO were divided into C–C/CC (284.2 eV), C–O (286.7 eV), and O–CO (288.2 eV) .…”

Section: Resultsmentioning

confidence: 96%

Corrosion Resistance of the GO/ZIF-8 Hybrid Loading Benzotriazole as a Multifunctional Composite Filler-Modified MgAlY Layered Double Hydroxide Coating

Chen

Dai

et al. 2022

Langmuir

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A composite coating with good load-carrying and controlled release capabilities for the corrosion inhibitor benzotriazole (BTA) was prepared while providing active and passive corrosion protection for magnesium alloy systems. In this paper, the organic corrosion inhibitor BTA was loaded into the ZIF-8/GO hybrid (GZB), and then, the GZB composite was coated with hexadecyltrimethoxysilane (HDTMS). Then, the GZB composites carried by HDTMS were made to adhere a ternary MgAlY layered double hydroxide (LDH) coating based on microarc oxidation (MAO) coating by electrophoresis (Si-MgAlY LDH coating). The successful loading of BTA by GZB composites was verified by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). Meanwhile, the Si-MgAlY LDH coating was characterized by X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. The potentiodynamic polarization curves show that the corrosion current density of the Si-MgAlY LDH coating reaches (2.08 ± 0.49) × 10–9 A/cm2, which means that the Si-MgAlY LDH coating greatly improves the corrosion resistance of magnesium alloy AZ31. The Si-MgAlY LDH coating can also achieve self-healing function in harsh environments, which is attributed to the synergistic effect of passive and active protection. The composite coating is of great significance to expand the potential applications of magnesium alloys.

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Section: Resultsmentioning

confidence: 96%

Corrosion Resistance of the GO/ZIF-8 Hybrid Loading Benzotriazole as a Multifunctional Composite Filler-Modified MgAlY Layered Double Hydroxide Coating

Chen

Dai

et al. 2022

Langmuir

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“…Compared with MOFs, which are frequently used as DDS, 177–183 POP-based DDS are more safe. In particular, because of their metal components, MOFs can be toxic or have low biocompatibility.…”

Section: Advantages Of the Porous Organic Polymers For Drug Deliverymentioning

confidence: 99%

Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties

et al. 2022

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“…The unique properties of this MOF stimulated the development of flexible ZIF-8-based platforms for the drug delivery of small-molecule and macromolecular therapeutics [ 9 ]. ZIF-8 exhibits pH-controllable drug release, high efficiency of endosomal escape, and good biocompatibility [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. The surface of ZIF-8 particles is modifiable by targeting agents, providing a higher efficiency of nanoparticle-based therapy [ 19 , 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Stability of ZIF-8 Nanoparticles in Most Common Cell Culture Media

et al. 2022

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Zeolite imidazolate framework-8 (ZIF-8) is a promising platform for drug delivery, and information regarding the stability of ZIF-8 nanoparticles in cell culture media is essential for proper interpretation of in vitro experimental results. In this work, we report a quantitative investigation of the ZIF-8 nanoparticle’s stability in most common cell culture media. To this purpose, ZIF-8 nanoparticles containing sterically shielded nitroxide probes with high resistance to reduction were synthesized and studied using electron paramagnetic resonance (EPR). The degradation of ZIF-8 in cell media was monitored by tracking the cargo leakage. It was shown that nanoparticles degrade at least partially in all studied media, although the degree of cargo leakage varies widely. We found a strong correlation between the amount of escaped cargo and total concentration of amino acids in the environment. We also established the role of individual amino acids in ZIF-8 degradation. Finally, 2-methylimidazole preliminary dissolved in cell culture media partially inhibits the degradation of ZIF-8 nanoparticles. The guidelines for choosing the proper cell culture medium for the in vitro study of ZIF-8 nanoparticles have been formulated.

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A pH-responsive hydrophilic controlled release system based on ZIF-8 for self-healing anticorrosion application

Cited by 108 publications

References 50 publications

Corrosion Resistance of the GO/ZIF-8 Hybrid Loading Benzotriazole as a Multifunctional Composite Filler-Modified MgAlY Layered Double Hydroxide Coating

Corrosion Resistance of the GO/ZIF-8 Hybrid Loading Benzotriazole as a Multifunctional Composite Filler-Modified MgAlY Layered Double Hydroxide Coating

Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties

Stability of ZIF-8 Nanoparticles in Most Common Cell Culture Media

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