A Perspective of Simian Tuberculosis in the United States - 1972

Abstract

Despite the availability of effective control measures, simian tuberculosis continues to be a major colony management problem. In 1972, 909 cases of simian tuberculosis were reported to the Center for Disease Control. Most of the cases (838) were in rhesus monkeys (Macaco mulatta). The attack rate was higher for animals conditioned by commercial importers prior to sale (6.6%) than for animals received shortly after importation without conditioning (1.2%). Failure to apply control measures effectively and consistently both in trade channels and at the user level is a significant factor in perpetuation of the problem.

REVIEW PAPER: Emerging and Reemerging Infectious Diseases of Nonhuman Primates in the Laboratory Setting

“…144 Many similar scenarios have been reported and so underscore the difficulties inherent in screening for disease and containing the outbreak once an infected animal is identified. 47,64,93 Both New World and Old World species are susceptible. Most reports of mycobacteriosis in Old World animals involve rhesus and cynomolgus macaques, but African monkeys and great apes are susceptible as well.…”

“…Most reports of mycobacteriosis in Old World animals involve rhesus and cynomolgus macaques, but African monkeys and great apes are susceptible as well. 64 Sporadic cases of pulmonary and disseminated mycobacteriosis have been reported in owl monkeys, squirrel monkeys, and capuchins, but these species are believed to be relatively resistant. 60,68,123 Clinical disease.…”

Infection in Rhesus (Macaca mulatta) and Squirrel (Saimiri sciureus) Monkeys due to Mycobacterium tuberculosis Phage Type B

“…Significant advances have been made in the control of tuberculosis in primate colonies, particularly since 1960, yet this disease remains a com mon problem among nonhuman primates maintained for scientific pur poses in institutions throughout the country [1]. Between November 17 and December 11,1975, 18 monkeys at the Medical College of Virginia (MCV) either died with tuberculosis or were euthanized because of a positive tuber culin test.…”