This review analyzes the implications of social engagement versus isolation to wellbeing and among individuals with Autism Spectrum Disorder (ASD), more specifically influences of social interventions, opportunities for involvement in social activities (i.e., skills training, vocational programs, sports, and community engagements), social media use, and mobile apps. All of which offer an opportunity for social interaction that may not be feasible under typical circumstances. It questions how these social influences affect the well-being and adjustment of individuals with ASD. It is important to consider how these forms of social engagement relate to the well-being of individuals with ASD, especially because of the increasing amount of literature that has suggested better outcomes for individuals with ASD who are presented with opportunities for social engagement. This review will be directed through the analysis of literature relative to improvements to well-being resulting from different areas of social engagement. Its goal is to bring awareness to and increase the amount of knowledge regarding the significance of social engagement, and how it is essential to overall well-being and social adjustment. This can be useful information for clinicians and counselors to consider in their work with individuals on the spectrum who may be seeking their help or support.