Lacrimation or epiphora is one of the most common complaints in pediatric ophthalmic practice, indicating the presence of lacrimal duct obstruction. It is customary to distinguish between congenital or primary obstruction of the nasolacrimal duct the most common cause of lacrimation in newborns and children in the first year of life. Secondary or acquired dacryostenosis, characteristic of children from one year and older, most often has a rhinogenic origin, is more difficult to treat, and often leads to the development of complicated forms of the disease. Assessment of the cause of the epiphora is the key to making the correct diagnosis and choosing the optimal treatment tactics, conservative and/or surgical. A multidisciplinary approach, the interaction of an otorhinolaryngologist and an ophthalmologist is of great importance, which ensures the final successful result of lacrimation treatment in children.