A numerical analysis of forces imposed on particles in conventional dielectrophoresis in microchannels with interdigitated electrodes

Numerical modeling of motion trajectory and deformation behavior of a cell in a nonuniform electric field

“…At the electric frequency f = 1 MHz, the levitation heights of the latex beads with radii of 0.5 and 2.0 m are plotted in Fig. 1 and then compared with the numerical results of Cao et al 28 Here, a good agreement between them is achieved, although the deformation of the latex beads is considered in the present model. However, the radius of the latex beads is significantly smaller than the channel width, such that the deformation of latex beads is negligibly small.…”

“…The mathematical model is validated by comparing the present simulation results with the previously published numerical predictions by Cao et al, 28 where the levitation height of the latex beads was measured as a function of the applied potential at the electrodes. The parameter values reported by Cao et al 28 for the permittivity and conductivity of the latex beads and suspending fluid, b = 2.55 0 ͑ 0 is the vacuum permittivity͒, b = 0.2 mS/ m, f =78 0 , and f =10 mS/ m, are also used in the present validation without modification.…”

“…The parameter values reported by Cao et al 28 for the permittivity and conductivity of the latex beads and suspending fluid, b = 2.55 0 ͑ 0 is the vacuum permittivity͒, b = 0.2 mS/ m, f =78 0 , and f =10 mS/ m, are also used in the present validation without modification. At the electric frequency f = 1 MHz, the levitation heights of the latex beads with radii of 0.5 and 2.0 m are plotted in Fig.…”

Predicting and eliminating Joule heating constraints in large dielectrophoretic IDE separators

“…By this means, wall effects and disturbances induced by the edges of the electrodes are negligible, since the length of electrodes is much larger than electrode diameter. Besides, the periodical array of electrodes allows to simplifying the whole system with one representative group of electrodes for simulation (Cao et al, 2008). Further, both alternating current (ac) input voltage and direct current (dc) voltage, equivalent to the root mean squared voltage (U rms ) of the ac input were applied.…”

A capillary dielectrophoretic chip for real-time blood cell separation from a drop of whole blood

“…ACETF induces the fluid flow because of the joule heating of the fluid produces a temperature gradient in the conductivity solution, 46 which must be manipulated in the high conductivity solution (>0.1 S/m) and high frequency ($MHz). 32,[35][36][37][38]47 Too high temperature can cause the blood cells breach and produce the phenomenon of hemolysis. Therefore, we were operated in the low-frequency (100 kHz) and the appropriate voltage to reduce the electrothermal effect and achieve micro mixed effect.…”