A novel ultrasound instrument for investigation of arterial mechanics

Bambi, G.; Morganti, T.; Ricci, Stefano; Boni, Enrico; Guidi, Francesco; Palombo, Carlo; Tortoli, Piero

doi:10.1016/j.ultras.2003.11.008

Cited by 45 publications

(30 citation statements)

References 17 publications

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“…4 Using multigate Doppler measurements, the blood flow velocity profile and blood flow velocity gradient at the wall edge were determined from longitudinal (along the blood flow directions) views of blood vessels. [5][6][7][8] Dae Woo Park, PhD, Grant H. Kruger, PhD, Jonathan M. Rubin, MD, PhD, James Hamilton, PhD, Paul Gottschalk, PhD, Robert E. Dodde, PhD, Albert J. Shih, PhD, William F. Weitzel, MD Received January 1, 2013, This study investigated the use of ultrasound speckle decorrelation-and correlationbased lateral speckle-tracking methods for transverse and longitudinal blood velocity profile measurement, respectively. By studying the blood velocity gradient at the vessel wall, vascular wall shear stress, which is important in vascular physiology as well as the pathophysiologic mechanisms of vascular diseases, can be obtained.…”

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confidence: 99%

Quantification of Ultrasound Correlation‐Based Flow Velocity Mapping and Edge Velocity Gradient Measurement

Park

Kruger

Rubin

et al. 2013

J of Ultrasound Medicine

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he blood flow velocity profile is important for diagnosis of cardiovascular diseases, which are associated with abnormal blood flow in arteries due to hemodynamic changes in patients. 1 The blood flow velocity gradient at the wall edge has been used to estimate the vascular wall shear stress, which has a key role in vascular physiology as well as the pathophysiologic mechanisms of vascular diseases. 2 Based on Poiseuille theory, the blood flow velocity profile is parabolic, and high-velocity gradients occur at the vascular wall in steady-state and fully developed laminar flow in normal conduit vessels. 3 In areas with vascular tortuosity, branching, and the presence of vascular plaque, the blood flow velocity profile is asymmetric. 1 Ultrasound imaging has been the preferred noninvasive technique for measuring blood flow velocity profiles.Multigate Doppler ultrasound measurement has been applied to estimate the blood flow velocity in vessels. 4 Using multigate Doppler measurements, the blood flow velocity profile and blood flow velocity gradient at the wall edge were determined from longitudinal (along the blood flow directions) views of blood vessels. [5][6][7][8] Dae Woo Park, PhD, Grant H. Kruger, PhD, Jonathan M. Rubin, MD, PhD, James Hamilton, PhD, Paul Gottschalk, PhD, Robert E. Dodde, PhD, Albert J. Shih, PhD, William F. Weitzel, MD Received January 1, 2013, This study investigated the use of ultrasound speckle decorrelation-and correlationbased lateral speckle-tracking methods for transverse and longitudinal blood velocity profile measurement, respectively. By studying the blood velocity gradient at the vessel wall, vascular wall shear stress, which is important in vascular physiology as well as the pathophysiologic mechanisms of vascular diseases, can be obtained. Decorrelationbased blood velocity profile measurement transverse to the flow direction is a novel approach, which provides advantages for vascular wall shear stress measurement over longitudinal blood velocity measurement methods. Blood flow velocity profiles are obtained from measurements of frame-to-frame decorrelation. In this research, both decorrelation and lateral speckle-tracking flow estimation methods were compared with Poiseuille theory over physiologic flows ranging from 50 to 1000 mm/s. The decorrelation flow velocity measurement method demonstrated more accurate prediction of the flow velocity gradient at the wall edge than the correlation-based lateral speckle-tracking method. The novelty of this study is that speckle decorrelation-based flow velocity measurements determine the blood velocity across a vessel. In addition, speckle decorrelation-based flow velocity measurements have higher axial spatial resolution than Doppler ultrasound measurements to enable more accurate measurement of blood velocity near a vessel wall and determine the physiologically important wall shear.

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confidence: 99%

Quantification of Ultrasound Correlation‐Based Flow Velocity Mapping and Edge Velocity Gradient Measurement

Park

Kruger

Rubin

et al. 2013

J of Ultrasound Medicine

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“…From the multigate acquisition of the spatial velocity distribution, the 1D wall shear rate is derived according to τ = µ ∂v ∂r via numerical differentiation of the velocity profiles [8], [9].…”

Section: Wall Shear Ratementioning

confidence: 99%

The multigate Doppler approach for assessing hemodynamics in a forearm vascular access for hemodialysis purposes

Swillens

Canneyt

Segers

et al. 2013

2013 IEEE International Ultrasonics Symposium (IUS)

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Abstract-We compared the multigate and single gate pulsed wave Doppler (PWD) approach to assess the hemodynamics in an arteriovenous fistula for hemodialysis purposes. In particular, we evaluated volume flow and wall shear rate measurements based on PWD because: (i) volume flow measurements are typically performed to assess the maturation of the arteriovenous fistula (AVF), with low postoperative fistula flow being a prognostic marker for failure of the AVF; (ii) wall shear stress may play an important role in vascular remodeling processes of the fistula. As in-vivo validation of fistula flow measurements is cumbersome, we performed simulations integrating computational fluid dynamics with an ultrasound (US) simulator. Flow in the arm was calculated, based on a patient-specific model of the arm vasculature pre and post AVF creation. Next, raw ultrasound signals were simulated and processed using a multigate and single gate Doppler approach in the radial artery, both for the preop and postop setting. Results showed that the extreme postop flow conditions (high velocity magnitudes and complex flow profiles) hampered accurate assessment of both wall shear rate and volume flow, while reasonable estimates were obtained preop (lower velocity magnitudes and laminar flow).

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“…The latter value is well better than the spatial resolution required to suitably track the spatial velocity variations typically present in human arteries (Nichols and O'Rourke, 1998). The power spectral density of the Doppler signal corresponding to each gate was computed, and the local mean velocity was estimated from the spectrum's first moment (Bambi et al, 2004). For each gate, over each pulsating cycle, approximtely 70 velocity values were obtained.…”

Section: B Ultrasound Equipmentmentioning

confidence: 99%

Estimation of the viscoelastic properties of vessel walls using a computational model and Doppler ultrasound

et al. 2010

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A novel ultrasound instrument for investigation of arterial mechanics

Cited by 45 publications

References 17 publications

Quantification of Ultrasound Correlation‐Based Flow Velocity Mapping and Edge Velocity Gradient Measurement

Quantification of Ultrasound Correlation‐Based Flow Velocity Mapping and Edge Velocity Gradient Measurement

The multigate Doppler approach for assessing hemodynamics in a forearm vascular access for hemodialysis purposes

Estimation of the viscoelastic properties of vessel walls using a computational model and Doppler ultrasound

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